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2022 Arizona Cardinals Team Futures Odds, Picks, and Preview: Win Total, Player Prop, and Playoff Predictions

Mike Spector

Last Updated: July 18, 2022 6:26 AM EDT • 2 min 46 sec read.

INGLEWOOD, CALIFORNIA - JANUARY 17: Kyler Murray #1 of the Arizona Cardinals walks off the field after losing to the Los Angeles Rams 34-11 in the NFC Wild Card Playoff game at SoFi Stadium on January 17, 2022 in Inglewood, California. Ronald Martinez/Getty Images/AFP (Photo by RONALD MARTINEZ / GETTY IMAGES NORTH AMERICA / Getty Images via AFP)

The Arizona Cardinals ended a six-year playoff drought last season with a wild-card berth but lost to the eventual Super Bowl champion Los Angeles Rams in the first round. Check out the Cardinals' futures odds, picks, and preview for the upcoming season.

A wild-card round playoff exit was disappointing for a Cardinals team that started the 2020 season with a 7-0 record for the first time since 1974. However, Arizona went 5-6 down the stretch as injuries took their toll, namely with Kyler Murray missing three games and DeAndre Hopkins playing in a total of only 10 games.

Arizona's futures odds entering this season took a slight hit when Hopkins was suspended six games for violating the league's performance-enhancing drug policy. Can the Cardinals hold down the fort and be successful in his absence?

Here’s our 2022 NFL season preview for the Arizona Cardinals with a look at the team’s futures markets and our top picks (odds via BetMGM and FanDuel Sportsbook).

Arizona Cardinals' 2022 Futures Odds

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Arizona Cardinals 2022 Picks

Under 8.5 wins (-105 via BetMGM)To miss the playoffs (-115 via BetMGM)To start 0-4 (+700 via BetMGM)Marquise Brown Over 875.5 receiving yards (-112 via FanDuel)

Under 8.5 Wins (-105)

Arizona's late-season issues have surfaced in all three years under Kingsbury. From 2019 to 2021, the Cardinals are a combined 15-5-1 in their first seven games. However, from the eighth game on, Arizona is just 9-19.

These issues also were consistent with Kingsbury's Texas Tech teams. From 2013 to 2018, his Red Raiders went 27-15 through the first seven games and finished 8-25 collectively from the eighth to the end of the season. Thus, Kingsbury's losing record in the second half of each season suggests opponents figure out his offensive schemes, and there are not a lot of adjustments made.

Arizona's offense also has a much lower ceiling without Hopkins, so the Cardinals should struggle even before getting to the latter part of the season.

Check out the latest comprehensive and most trusted Sportsbook Reviews by SBR.

To Miss The Playoffs (-115)

Arizona backers will be optimistic that the team can offset Hopkins' absence with the draft-day trade for Marquise Brown, Murray's teammate at Oklahoma. However, Murray relies so much on Hopkins's elite size as a safety net when he is in trouble, and his numbers are vastly different with him on the field vs. off the field.

Murray is 8-2 with Hopkins on the field, with a total QBR of 64 and a 19:9 touchdown to interception ratio. In five games without Hopkins, Murray has won just one start, and his total QBR drops to 37 to go along with five touchdowns to three picks.

Given that Kingsbury's teams typically get off to hot starts, it may be difficult for the Cardinals to adjust to a rare poor opening to the campaign.

To Start 0-4 (+700)

Even with a healthy Hopkins, Arizona was likely starting 0-3, anyway. The Cardinals kick off the season at home against the Kansas City Chiefs, travel to Las Vegas to face the retooled Raiders, and then host the juggernaut Rams.

FPI doesn't give Arizona better than a 52% chance to win any of those games. The key to this bet will be a road date with the Panthers in the fourth game, but Carolina could improve in all facets with a healthy quarterback competition between Baker Mayfield and Sam Darnold.

It's also worrisome that Murray didn't attend all the team's OTAs and removed all social media references to the Cardinals in February. He wants a long-term deal, but if that doesn't get negotiated, Arizona's season could snowball fast if it starts 0-3.

Brown Over 875.5 Receiving Yards (-112)

Arizona expects big things from "Hollywood" after giving up a first-round pick to get him. He's coming off a 1,008-yard receiving season with the run-first Ravens and hooked up for 74 catches, 1,312 yards, and 10 touchdowns with Murray during their college days.

With Murray's ability to extend plays, Brown's elite speed will come in handy, as he is difficult to cover for long stretches. And with Hopkins missing the first six games, Brown will be thrust into a more prominent role early.

Where to Bet on Arizona Cardinals Futures

Here are our top-rated sportsbooks:

FanDuel SportsbookCaesars SportsbookDraftKings SportsbookPointsBetBetMGM

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Cardinals 2022 odds, picks, and preview made on 7/18/2022 at 8:42 a.m. ET

Written By:
Mike Spector
I have been in the sports writing industry for over three years, working for sites like BettingPros/FantasyPros, Oddschecker, and Sportsbook Review. In my first year writing for BettingPros, I finished with the #2 overall record in their annual NFL betting competition, which made picks against the spread, and from an over/under and moneyline perspective. I am an avid fan of the NFL, MLB, and all college sports. In my opinion, March Madness is the best sporting event there is, and I am especially euphoric starting with conference tournament time in college basketball. I am a big advocate of "fading the public" and making plays that are contrarian, constantly citing that "there are reasons why they have those big shiny buildings in Las Vegas." Follow me on Twitter for my best bets and commentary to go along with the wagers.