Skip to main content
Los Angeles Rams' Von Miller holds up the trophy after winning Super Bowl LVI against the Cincinnati Bengals at SoFi Stadium in Inglewood, California, on February 13, 2022. (Photo by Frederic J. Brown / AFP)

The National Football League announced its full schedule last Thursday, and the oddsmakers wasted little time putting out point spreads for every game.  

Here is a look at four regular-season matchups that could be potential Super Bowl previews during the 2022 season. 

Check out the latest comprehensive and most trusted Sportsbook Reviews by SBR here

Here are four potential Super Bowl previews, with point spreads via DraftKings, from the 2022 NFL schedule. 

Bills (+1) vs. Rams – Week 1 

A sensational opener to the 2022 regular season, with last season's champs, the Los Angeles Rams, hosting this season's Super Bowl favorite, the Buffalo Bills. 

Bills quarterback Josh Allen has emerged as an elite quarterback in the past two seasons, and that will get a team into the championship discussion.  

https://twitter.com/billbarnwell/status/1487128962354528257?s=20&t=QOTEgTh15mH4gLaIB485ig

The Rams bring back the core of their championship squad, including defensive tackle Aaron Donald, cornerback Jalen Ramsey, wide receiver Cooper Kupp, and quarterback Matthew Stafford.  

Chiefs (+2.5) vs. Buccaneers – Week 4 

Even though the Chiefs traded wide receiver Tyreek Hill to Miami, it isn't easy to count them out when they have superstar quarterback Patrick Mahomes and tight end Travis Kelce. 

The Chiefs have brought in receivers JuJu Smith-Schuster, Marquez Valdes-Scantling, and rookie Skyy Moore to offset the effects of Hill's departure. 

The Bucs might not have been in the championship hunt, but when Tom Brady decided to return, that changed the calculation, and the Bucs now have the shortest Super Bowl odds in the NFC. 

https://twitter.com/PFF/status/1436159979254333440?s=20&t=QOTEgTh15mH4gLaIB485ig

Packers (+4) vs. Bills – Week 8 

Packers quarterback Aaron Rodgers has won back-to-back MVP awards, and even if his playoff history has its share of disappointment, the odds are that the Packers – coming off three straight 13-win seasons – will be contenders. 

https://twitter.com/BookOfEli_NFL/status/1498005737296973825?s=20&t=QOTEgTh15mH4gLaIB485ig

They will face the Bills, a team on the rise and the team with big expectations coming into the season. The Bills benefit from coming off a bye week for this Sunday night game at home.  

Rams (+1.5) vs. Chargers – Week 17 

As noted above, the defending-champion Rams have the elite talent to contend again this season and have a compelling late-season matchup against their fellow SoFi Stadium inhabitants. 

The Chargers did not make the playoffs last season, but they are not that far off the championship path, partly because quarterback Justin Herbert appears to be a rising star and might have what it takes to lift the Chargers to another level. If both teams are contenders, this could be a great late-season test. 

https://twitter.com/FDSportsbook/status/1470159149002592257?s=20&t=QOTEgTh15mH4gLaIB485ig

Here are the latest Super Bowl odds from DraftKingsFanDuel, and Caesars

https://datawrapper.dwcdn.net/FRNm7/1/

Make sure to keep an eye on our Live Odds page throughout the week to get the best lines possible and connect with others in the SBR community on our popular sports betting forum