How many points are CFB injuries worth?

[bettingman6]

Let's say that a CFB team announced that all of their starters are injured and they are playing their entire second string in the next game. How much is the betting line affected?

Assume that this team has average starters and average backups.

[Husker36]

They would probably take that game completely off the board. But to entertain you..... I'd say 10-14 points.