| Fri., 9/14/12 | 9:00 PM | Washington State | UNLV | ESPN |
| Sat., 9/15/12 | 12:00 PM | California | Ohio State | ABC |
| 12:00 PM | Wake Forest | FSU | ESPN | |
| 12:00 PM | Arkansas State | Nebraska | ESPN2 | |
| 12:00 PM | Virginia Tech | Pittsburgh | ESPNU | |
| 12:00 PM | Western Michigan | Minnesota | BTN | |
| 12:00 PM | Charleston Southern | Illinois | BTN | |
| 12:00 PM | Eastern Michigan | Purdue | BTN | |
| 12:00 PM | William & Mary | Towson | NBCSN | |
| 12:00 PM | Northern Illinois | Army | CBSSN | |
| 12:00 PM | TCU | Kansas | FX | |
| 12:00 PM | Louisiana-Lafayette | Oklahoma State | FSN | |
| 12:20 PM | Louisiana-Monroe | Auburn | SECN | |
| 12:30 PM | Presbyterian | Vanderbilt | CSS | |
| 3:00 PM | Tennessee Tech | Oregon | Pac-12 | |
| 3:30 PM | North Carolina | Louisville | ABC or ESPN2 | |
| Navy | Penn State | |||
| 3:30 PM | Virginia | Georgia Tech | ESPNU | |
| 3:30 PM | Alabama | Arkansas | CBS | |
| 3:30 PM | ECU | Southern Miss | CBSSN | |
| 3:30 PM | Texas A&M | SMU | FSN | |
| 3:30 PM | Massachusetts | Michigan | BTN | |
| 3:30 PM | Northern Iowa | Iowa | BTN | |
| 3:30 PM | Boston College | Northwestern | BTN | |
| 4:00 PM | Portland State | Washington | FX | |
| 4:00 PM | Miami (OH) | Boise State | NBCSN | |
| 6:00 PM | Florida | Tennessee | ESPN | |
| 7:00 PM | Arizona State | Missouri | ESPN2 | |
| 7:00 PM | Western Kentucky | Kentucky | ESPNU | |
| 7:00 PM | North Texas | Kansas State | FSN | |
| 7:30 PM | USC | Stanford | FOX | |
| 7:30 PM | Florida Atlantic | Georgia | CSS | |
| 8:00 PM | Notre Dame | Michigan State | ABC | |
| 8:00 PM | Colorado | Fresno State | CBSSN | |
| 8:00 PM | Utah State | Wisconsin | BTN | |
| 8:00 PM | Ball State | Indiana | BTN | |
| 9:15 PM | Texas | Mississippi | ESPN | |
| 10:00 PM | BYU | Utah | ESPN2 | |
| 10:30 PM | South Carolina State | Arizona | Pac-12 | |
| 10:30 PM | Houston | UCLA | Pac-12 |
Enjoy the games, boys!
Kick some ASSSSSSSS this weekend!
Pacooooooooooooooooooooooooooooooooooooo oooooo!