| Date | Game/Spread |
| Aug. 28 | Wake Forest (-7.5) at UL-Monroe |
| Aug. 28 | Mississippi (-8.5) vs. Boise State* |
| Aug. 28 | Texas A&M at South Carolina (-9) |
| Aug. 28 | Temple at Vanderbilt (-21) |
| Aug. 29 | BYU (-14) at Connecticut |
| Aug. 30 | Colorado State (Pick 'em) vs. Colorado* |
| Aug. 30 | Penn State (-3.5) vs. Central Florida* |
| Aug. 30 | Ohio State (-17.5) at Navy |
| Aug. 30 | Rice at Notre Dame (-21) |
| Aug. 30 | West Virginia vs. Alabama (-22.5)* |
| Aug. 30 | Oklahoma State vs. Florida State (-17)* |
| Aug. 30 | LSU (-3) vs. Wisconsin* |
| Aug. 30 | Arkansas at Auburn (-21.5) |
| Aug. 30 | Clemson at Georgia (-7) |
| Aug. 30 | Fresno State at USC (-17.5) |
| Aug. 31 | Utah State at Tennessee (-6.5) |
| Sept. 1 | Miami at Louisville (-3.5) |