Saturday, April 5, 2008
| 1:05 PM | 951 | San Francisco Giants, Kevin Correia | o8.5 -105 | +168 |
| - | 952 | Milwaukee Brewers, Manny Parra | u8.5 -115 | -180 |
| 1:05 PM | 953 | Houston Astros, Roy Oswalt | o | -109 |
| - | 954 | Chicago Cubs, Jason Marquis | u | -101 |
| 1:10 PM | 955 | Philadelphia Phillies, Adam Eaton | o9.5 -120 | +141 |
| - | 956 | Cincinnati Reds, Aaron Harang | u9.5 EVEN | -151 |
| 1:10 PM | 957 | Washington Nationals, Matt Chico | o8.5 -105 | +144 |
| - | 958 | St. Louis Cardinals, Adam Wainwright | u8.5 -115 | -154 |
| 3:55 PM | 959 | New York Mets, Mike Pelfrey | o9.5 EVEN | +108 |
| - | 960 | Atlanta Braves, Tom Glavine | u9.5 -110 | -113 |
| 3:55 PM | 961 | Los Angeles Dodgers, Brad Penny | o6.5 -120 | +122 |
| - | 962 | San Diego Padres, Jake Peavy | u6.5 EVEN | -132 |
| 7:10 PM | 963 | Pittsburgh Pirates, Paul Maholm | o9.5 EVEN | +108 |
| - | 964 | Florida Marlins, Mark Hendrickson | u9.5 -120 | -118 |
| 8:05 PM | 965 | Arizona Diamondbacks, Brandon Webb | o8 -110 | -112 |
| - | 966 | Colorado Rockies, Jeff Francis | u8 -110 | +102 |
| 1:05 PM | 967 | Tampa Bay Rays, Edwin Jackson | o10.5 -120 | +188 |
| - | 968 | New York Yankees, Andy Pettitte | u10.5 EVEN | -205 |
| 1:07 PM | 969 | Boston Red Sox, Clay Buchholz | o9 -105 | -124 |
| - | 970 | Toronto Blue Jays, Jesse Litsch | u9 -115 | +114 |
| 2:10 PM | 971 | Kansas City Royals, Gil Meche | o8 -110 | -105 |
| - | 972 | Minnesota Twins, Livan Hernandez | u8 -110 | -105 |
| 3:55 PM | 973 | Chicago White Sox, Gavin Floyd | o10 -115 | +148 |
| - | 974 | Detroit Tigers, Dontrelle Willis | u10 -105 | -158 |
| 4:05 PM | 975 | Cleveland Indians, C.C. Sabathia | o8.5 EVEN | -154 |
| - | 976 | Oakland Athletics, Dana Eveland | u8.5 -120 | +144 |
| 7:05 PM | 977 | Seattle Mariners, Miguel Batista | o9.5 -110 | +102 |
| - | 978 | Baltimore Orioles, Adam Loewen | u9.5 -110 | -112 |
| 9:05 PM | 979 | Texas Rangers, Kevin Millwood | o8.5 -130 | +144 |
| - | 980 | Los Angeles Angels, Jered Weaver | u8.5 +110 | -154 |
