Newcastle vs. Liverpool Prediction, Picks & Odds for Sunday's Premier League Match
The opening weekend of the 2026-27 Premier League season concludes on Sunday with a heavyweight clash between Newcastle and Liverpool at St James' Park (11:30 a.m. on NBC, Peacock, and Telemundo). Although the Magpies have impressed at home, my Newcastle vs. Liverpool prediction backs the visitors to emerge victorious in Newcastle.
Liverpool are -112 favorites to open the season with a win against +300 Newcastle, with the Draw lying at +270 on the three-way moneyline. We also break down how Alexander Isak is going to haunt his old club as part of our Premier League best bets.
⚽ Newcastle vs. Liverpool predictions & best bets
See our experts' soccer picks.
| 💰 Best bets | 📊 Best odds | ⚖️ Wager (units) |
|---|---|---|
| Liverpool moneyline | -112 via bet365 | 1.75 units to profit 1.56 units |
| Alexander Isak anytime goalscorer | +130 via FanDuel | 0.75 units to profit 0.98 units |
| Both teams to score: yes | -225 via bet365 | 1.25 units to profit 0.56 units |
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💰 Newcastle vs. Liverpool best bet
Check out all of our soccer betting analysis and expert predictions this season.
Liverpool ML (-112)
St James' Park is never an easy assignment for visitors. But Liverpool could be poised to leave with three points after a miserable summer in the transfer market that has left Newcastle in brutal shape to open the season.
After losing a handful of key players, expect the Magpies to struggle to control the pace on their way to dropping points against the superior Reds.
Although Liverpool are still trying to replace club legend Mohamed Salah, the Reds will rely on stars like former Newcastle striker Alexander Isak and Florian Wirtz to be difference-makers in what should be a cagey match in hostile territory.
Score Prediction: Liverpool 2, Newcastle 1
🆚 SBR Edge: Newcastle's brutal summer
It’s been a summer to forget for Newcastle. From club icons leaving to players rejecting transfers to the north east of England, Newcastle have become the butt of endless jokes on social media due to their inability to keep - and attract - top talent.
Although Newcastle are in talks with teams to replace departed former captain Bruno Guimaraes, Sandro Tonali and Anthony Gordon, the team has been unable to recruit the necessary talent to give it a chance against Liverpool.
🔥 More Newcastle vs. Liverpool expert picks
Alexander Isak anytime goal (+130)
If this summer hasn’t been bad enough, it could get even worse if Alexander Isak rubs salt in the wounds of his former team with a goal on Sunday.
A year after his high-profile exit from Newcastle to join Liverpool for a record fee, Isak will be inspired to put last season’s woes behind him with an inspired performance at a stadium where he scored 25 goals in 35 Premier League home games with Newcastle.
Although he has the shortest odds to score at +135, Isak is the most likely to find the back of the net given that he’ll be the focal point in Liverpool’s lethal attack.
Amar Dedic to be booked (+300)
Newcastle’s newest signing Amar Dedic plays with an aggressive style that won’t go unnoticed by Sunday’s referee.
With the Newcastle right-back set to be tested down the wing, it might be wise to bet on him to get booked trying to contain the likes of Rio Ngumoha and Milos Kerkez.
The Bosnia and Herzegovina international picked up seven yellow cards in all competitions last season at Benfica, including a team-leading two red cards.
⚖️ Newcastle vs. Liverpool key stats
The stats below are from 2025-26
| Newcastle United | Liverpool | |
|---|---|---|
| Record | 14-7-17 | 17-9-12 |
| Home/Away Record | 10-2-7 | 10-6-3 |
| Goals for (xG) | 53 (58.12 xG) | 63 (61.35 xG) |
| Goals against (xGA) | 55 (51.28 xGA) | 53 (47.02 xGA) |
| Average possession | 56.2% | 52.4% |
📊 Newcastle vs. Liverpool odds
🆚 Newcastle vs. Liverpool projected lineups
Here are the projected lineups for Newcastle vs. Liverpool; subject to change:
| Newcastle (4-2-3-1) | Liverpool (4-2-3-1) |
|---|---|
| Hornicek | Alisson |
| Hall | Kerkez |
| Botman | Van Dijk |
| Thiaw | Jacquet |
| Dedic | Frimpong |
| Rasmey | Gravenberch |
| Bamba | Szoboszlai |
| Barnes | Gakpo |
| Wissa | Wirtz |
| Elanga | Ngumoha |
| Osula | Isaka |
📺 How to watch Newcastle vs. Liverpool
- Date: Sunday, Aug. 23
- Kickoff: 11:30 a.m. ET
- Location: St. James' Park (Newcastle-Upon-Tyne, England)
- TV/Streaming: NBC, Peacock, Telemundo
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