The list of the quarterbacks with the most pick-sixes in NFL history is a list of Hall of Famers and future Hall of Famers: Brett Favre is first with 31, Dan Marino and Joe Namath are tied for second with 28, and Drew Brees and Peyton Manning are tied for fourth with 27.
Aaron Rodgers has thrown just two pick-sixes in his career, while attempting 5,492 passes. That’s an incredibly low ratio