I grabbed 49ers +3800 at 5dimes on October 12th. Feel very good about the bet.
They have a very good chance of finishing second in the NFC. SF has only played 1 divisional game so far. They still have to play the seahawks, cardinals twice and rams twice.
At the price I got, there will be plenty of opportunity to hedge in the playoffs. Grabbing it now at +1000 doesn't have much value. Let's say the niners finish second, their road to the superbowl will be like this:
Divisional Home Game vs a team like Saints/Gaints line will be niners -3/PK
Conference Championship road game vs Packers line will be -7/8 (ML -300+)
Superbowl against AFC line will be AFC -6/7
It's safe to say they'll win the first game at home, but probably lose to Packers in GB. At that point, I would definitely hedge with GB moneyline which will be around -300. This is a steep price to pay only if you're getting +1000 with niners. Not to mention everything has to go perfect for them to even reach that point.