This is actually a hard one to predict.
The 49ers and Raiders offense are about even on Passing yards.
But the Raiders are better than the 49ers on Running yards.
http://espn.go.com/nfl/statistics/team/_/stat/total
Both the Raiders and 49ers have one of the worst run defense this year, but the Raiders are the better pass defense team than the 49ers.
Even last year the Raiders stopped the Eagles passing game and defeated the Eagles.
http://espn.go.com/nfl/statistics/te...sition/defense
Summary: Raiders have better Running offense and Passing defense than the 49ers, statistically.
If you look at the games so far for the 49ers. Games @ Home have been tight 3 points, while games Away the 49ers have been dominated.
If this is true, the Raiders and 49ers should have a tight game, if the 49ers win, the Raiders 6+ point should cover.
http://en.wikipedia.org/wiki/2010_Sa...o_49ers_season