Denver by 11
While one would think Manning vs Flacco is the determining factor here. I believe this game will be won in the trenches. Baltimore is not the run stopping defense they use to be and if you give Fox and Manning the ability to get big chunks of yardage on the ground its going to open up his Tight ends and receivers for big plays as well. While the Broncos definitely have the advantage of stopping the run and home field kicking advantage too. The case can be made that Broncos strength of schedule was soft but that has nothing to do with Manning or Fox and the goals they are seeking.
49rs by at least 4
No doubt Rogers and company want revenge and are facing a unproven QB who is yet to be proven in playoffs. The fact is niners dominate this game because they have the best pass defense at home. They only allow a average of 166 passing yards per game, fewest yards per catch, and hold opposing teams to the lowest passing first downs per game at home. The average opponent team pass rating is 74. This doesn't bold well for even Rogers and his multiple options. Green Bay ranks 28Th against yards per carry and that's a average of 4.5. The Niners have the thunder of Gore, the speed of James, and a well coached young QB. This is going to exploit the GB defense and eat the clock keeping Rogers watching for a majority of the game.
Seahawks by 10
I figure this to be one of the more lopsided games this weak. Again this game is going to be determined by the team that can run the ball effectively. Big advantage for Seahawks here. Atlanta is giving up 4.8 yards per rush and Seahawks average 4.9 per carry. Atlanta also loses the 3rd down battle and will struggle to get their defense off the field. Seahawks allow a league low 5.4 yards per completion and I just don't see how the Hawks are going to stop the run and keep thier defense from getting worn out by late in the game.
Houston by 3
Unlike last time I believe the attributes that Texans have will manifest themselves into a unthinkable road win at NE. While I do admit the NE defense is much better this year and Brady can be virtually unstoppable. I have to side with the team that is better equipped to run the ball effectively and chew up the clock. Houston leads the league in TOP which keeps the defense fresh and is a sign of a good running game that opens up play action. This won't be a popular play but I do believe Houston has all the ingredients to get to the Superbowl this year.
Good luck with whomever you chose.