Purdue has been playing excellent basketball lately. Not only that, the only road games they have lost this season are all to NCAA tourney teams besides Minny (Nolen was healthy for that game though, with Nolen, Minny is a tourney team).
I don't see anyway Purdue loses this game. It's still a Rivalry game (even though Indiana sucks) and they will be focused. They're trying to snatch up a 2 seed for the tournament.