I would never say anything is a lock, but USC -2.5 vs. Cal is about as close as you can get IMO. As a Cal fan I can tell you that the Bears do not play well against USC. Theyve lost 5 in a row, getting dominated in 4. They will stack the line to try to slow down Vareen, and Riley wont make enough plays. Infact, he'll prob throw a couple picks. On the flipside, Barkley is having an efficient year and the Trojans are putting up points. Book it now before the line moves. USC by 10+ in this one.