I've followed Clemson for years - don't see them winning by 45. Not with Auburn on the horizon. The starters will be out at halftime, and the backups (Tajh Boyd in particular) are simply not good enough to put up a ton of points.
Virginia Tech has beat JM 90-0 in the last two meetings. Saturday won't be any different. Take away the horrible first quarter against Boise, and the Hokies look strong.
Maryland showed flashes of a decent running game last week - for a quarter. They'll win easy, but not by 38.