I dont know which of these two bets i like the most so i am going to combine them in a little parlay.
Colts are missing key players, most notably, Ty Hilton. Patriots are banged offensively too, with Gronk and Gordon both questionable for the game. Whatever firepower they lose from missing either of these players, they will make up for that with the return of Julien Edleman. The weather in Foxborough MA around kick-off will be cloudy and a 25% chance of rain through the game. If it does rain, Patriots will enjoy the luxury of having James White and Sony Michel in the backfield. Rain will also bring in the Under. With both teams offense not looking great on offense and their offensive players banged up, I expect this one to go under. The Patriots is more fit to handle the elements and their depth will make Indianapolis unable to keep up with the Patriots/Historically Andrew Luck has never beaten Tom Brady, and the Patriots have beaten them 4 of the last 5 games with those games being won by more than ten points. All of these games have gone over but I dont think the offenses were missing or having so many players banged up.
Patriots - 30
Colts - 16
Pick - Parlay - Patriots -10 and under 51 pts -- 2.6 units to win 6.5