Talking to this dude at the casino that takes some bets on the games. I asked him if anyone beats the NFL. He laughed and said that in his entire history of any player that made more than 40 bets on NFL games during a season NEVER once finished "+" money.
Yeah, there might be the occasional weather related game you can bet under or some spot plays that might be worth while, but if your betting 3+ plays each and every week you stand no chance.