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Dillon Gabriel of the Oklahoma Sooners cuts back past safety Tyson Wilson of the UTEP Miners to score a 12-yard touchdown.
Dillon Gabriel of the Oklahoma Sooners cuts back past safety Tyson Wilson of the UTEP Miners to score a 12-yard touchdown. Photo by Brian Bahr/Getty Images/AFP.

What Kansas State-Oklahoma picks offer the best value when the two teams meet in Week 4 of the college football season?

The Oklahoma Sooners are 3-0 and ranked sixth in the nation. However, the Sooners have yet to play a worthy opponent.

That will change in Week 4 when they face Kansas State. The Wildcats are coming off a disappointing 17-10 loss to Tulane. Were they looking ahead to Oklahoma? And will the Sooners cruise in this one?

Here are our top picks for the Kansas State-Oklahoma college football Week 4 matchup (odds via BetMGM and PointsBet).

Kansas State vs. Oklahoma Picks

Check out the latest comprehensive and most trusted Sportsbook Reviews by SBR.

Kansas State vs. Oklahoma Spread Pick

Kansas State +13 (-110) ★★★

The Sooners have been gliding through 2022 so far, while the Wildcats are coming off a horrible home loss against Tulane. Yet most sportsbooks have been moving this line in favor of the Wildcats since opening at Oklahoma -13.

The Sooners seem like the obvious play, but this series has been close in recent matchups. One score or fewer has decided four of the last five contests, and the Sooners were 20-plus-point favorites in three of those games. These teams are more evenly matched than in recent years, which bodes well for the Wildcats.

Kansas State vs. Oklahoma O/U Pick

Under 53.5 (-110) ★★★

Over 60 points have been scored in each of the last five meetings between these teams. However, the Wildcats boast a defense that's allowing fewer than 10 points per game, and the Sooners' offense is weak by their standards. 

Yes, the Sooners are averaging 42.3 points per game, but who have they played? Oklahoma decimated Nebraska in Week 3. But the Sooners led just 7-3 at halftime against Kent State in Week 2. That inconsistency could hurt against the best defense they’ve played so far.

Kansas State vs. Oklahoma Prop Pick

Adrian Martinez Over 34.5 rushing yards (-115) ★★★★

Martinez has been more of a rusher than a passer since the beginning of his college football career, especially during significant games. He's rushed for 35-plus yards nine times over 13 matchups against ranked opponents.

Martinez recorded 34 rushing yards against Oklahoma in 2021, and this line is seemingly based on that. But the larger sample size throughout his collegiate career shows he's an effective runner. That includes averaging 47.7 yards per game in 2021, and a high of 57.2 in 2018.

Where to Bet on Kansas State-Oklahoma Picks

Here are our top-rated sportsbooks:

FanDuel Sportsbook
Caesars Sportsbook
DraftKings Sportsbook

SEE ALSO: All picksodds, and sports betting news. Be sure to check out’s community forums and betting tools.

Kansas State-Oklahoma picks made 9/22/2022 at 9:03 p.m. ET