Two of the easiest spots of the tournament for this round. Florida and Memphis are very undisciplined teams who won't be able to play the half court game required to beat Virginia and Saint Louis. Virginia ranks in the top 15 in the country at defending the 3 and Florida lives and die by it. Saint Louis has Rick Majerus, a veteran coach who will completely overmatch young "coach" Josh Pastner.
Saint Louis +4 against Memphis
Virginia +3.5 against Florida
Another game I like is Notre Dame. Xavier is a fraud who never deserved a bid. The "hot start" they got off to was defeating Georgia, winning at Vanderbilt in overtime, and slipping by Purdue at home by 3. Xavier was never that good and they will get beat by a Notre Dame team that is nothing to write home about either. They are a decent team who should cover the short number though. Cake walk for Duke to the Sweet 16, imagine that
Notre Dame -2.5 against Xavier
Other possible leans/plays
Harvard +6.5 (Just based on how bad Vandy is in the tourny and how smart Harvard plays)
UNLV -4.5 (Based on how lucky Colorado got to get in, everybody choked in that shithole of a conference)