Top Serie A Matchday 21 Betting Picks

Inter Milan manager Simone Inzaghi takes on former club Lazio in an eagerly anticipated showdown at the San Siro this weekend. Can the Nerazzurri avenge the defeat they suffered when these teams last met? We take a look at that game and more with our Serie A Matchday 21 picks.

Disastrous scenes played out across Italy on Thursday as local health authorities ordered four Serie A teams to quarantine.

In a ridiculous series of events, league leaders Inter turned up at Bologna's stadium to go through their prematch training drills despite knowing the game wouldn't go ahead due to a COVID-19 outbreak in the Bologna camp. Inter are set to be awarded a 3-0 win for the match.

Serie A also canceled Atalanta vs. Torino, Salernitana vs. Venezia, and Fiorentina vs. Udinese, and it's set to scrap matches featuring Torino, Bologna, and Udinese this weekend. We've provided picks on games that are expected to go ahead, but the situation could change.

Here are my top betting picks and predictions for the Serie A Matchday 21 schedule (odds via DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).

Serie A Matchday 21 Picks

AC Milan -1 (+105) Asian Handicap vs. Venezia ???Inter -1.25 (-105) vs. Lazio ???Verona -1.25 (-115) vs. Salernitana ???

SEE ALSO: All Soccer Picks

Serie A Matchday 21 Predictions

AC Milan -1 (+105) Asian Handicap

Milan pulled off an impressive 3-1 win against Roma on Thursday despite missing defenders Alessio Romagnoli and Fikayo Tomori due to COVID-19. Their squad is undoubtedly depleted, but their key forwards are fit and ready to go, so they should be able to outgun Venezia in this game.

Newly promoted Venezia have lost five of 10 away games this season, and they have a minus-11 goal differential on the road.

The reverse fixture finished 2-0 in favor of Milan, and the Rossoneri should be capable of a similarly comfortable win on Sunday.

Inter -1.25 (-105)

Inter's only defeat this season came against Lazio at the Stadio Olimpico back in October. That was a painful loss for manager Inzaghi, who left Lazio for Inter in the summer.

The Nerazzurri have 14 wins and four draws from their other 18 games this season and are on a seven-match winning streak. Additionally, they should be fresh following the aforementioned abandoned midweek game against Bologna.

Meanwhile, Lazio toiled to a 3-3 draw with Empoli and now own the fifth-worst defensive record in the league.

Inter are without only Hakan Çalhano?lu (suspended) and Edin Džeko (COVID-19) and should sweep Lazio aside to gain revenge for October's defeat.

Verona -1.25 (-115)

Verona surged to a strong 2-1 victory away at Spezia on Thursday to move up to 10th in the table. Only four teams in Serie A have scored more goals this season than Verona this season, and though their defense is a little suspect, Salernitana's is a lot worse.

Salernitana didn't play their midweek match against Venezia, so they'll be the fresher side. However, they still sit bottom of the table - 14 defeats from 18 games - and their away record is diabolical, so Verona should win this one comfortably.

Serie A Matchday 21 Quick Picks

https://datawrapper.dwcdn.net/a2ufL/1/

SEE ALSO: All picks and odds. Be sure to check out SportsbookReview.com's community forums and betting tools.

Serie A Matchday 21 picks made 1/7/2021 at 6:43 a.m. ET.