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â??â??â??â??â??â??â??MILAN, ITALY - NOVEMBER 7: Alexis Saelemaekers of AC Milan and Ivan Perisic of FC Internazionale in action during the Italian football Serie A championship match between AC Milan vs FC Internazionale at San Siro Stadium in Milan, Italy on November 07, 2021. Piero Cruciatti / Anadolu Agency (Photo by Piero Cruciatti / ANADOLU AGENCY / Anadolu Agency via AFP)

The Serie A season returns with lots of exciting clashes for Matchday 13, and we have picks and analysis on the action.

Napoli and AC Milan remain level on 32 points apiece at the top of the Serie A table. Both teams remain unbeaten on the season. They're seven points clear of third-place Inter Milan. The mighty Juventus is languishing in eighth place after a sluggish start to the season, and will be keen to return to winning ways.

Here are my top betting picks and predictions for the Serie A Matchday 13 schedule (odds via SI Sportsbook; pick confidence based on a 1-to-5-star scale).

Serie A Matchday 13 Picks

Lazio vs. Juventus – Both teams to score & Over 2.5 goals (+100) ???AC Milan to beat Fiorentina (+120) ???Roma to beat Genoa (-138) ????

SEE ALSO: Top Premier League Matchday 12 Picks

Serie A Matchday 13 Predictions

Lazio vs. Juventus – Both to score & Over 2.5 goals (+100)

Lazio boasts the best home record in Serie A at 5-1-0 through six games at Stadio Olimpico.

In that time, it has fired in 18 goals and conceded six, providing home fans with a great deal of entertainment.

This game will pit Lazio manager Maurizio Sarri against his former club, and he will be keen to show his former employers what they are missing.

Juventus was the preseason favorite to win the title, but it has underwhelmed thus far. Both teams to score has paid off in eight of its games, underscoring just how leaky its defense has been.

The Bianconeri are unlikely to keep a clean sheet against Lazio F Ciro Immobile and Co., in this game; however, they also have the quality to get on the score sheet.

AC Milan to beat Fiorentina (+120)

Fiorentina will be missing at least two important central defenders for this game. Nikola Milenkovi? and Lucas Martínez Quarta are both suspended.

Matija Nastasi? also suffered an injury while he was away with the Serbian national team last week, so he is in doubt. Fiorentina could therefore be plunged into a defensive crisis.

That does not augur well for a game against unbeaten AC Milan. It has five wins and a draw from six away matches so far this season.

Milan is the second highest-scoring team in the league, and it has recently welcomed forwards Zlatan Ibrahimovi?, Ante Rebi?, and Brahim Díaz back from injury. Milan should exploit this depleted Fiorentina defense.

Roma to beat Genoa (-138) 

Roma has lost four of six away games this season. Thay will be a cause of great consternation for manager José Mourinho.

He has had a two-week international break to figure out how to improve that record. This is a perfect game in which to do so.

Genoa has the worst home record in Serie A at 0-3-2 through five games at Luigi Ferraris Stadium.

It concedes an average of two goals per game. Roma really should capitalize on Genoa’s defensive vulnerabilities to win this match.

Serie A Matchday 13 Quick Picks

GamePickNotesInter vs. NapoliNapoli Draw no Bet (+145)The visitors have not lost a single game this season, and the odds on a win remain very tempting.Bologna vs. VeneziaBologna to Win (-150)Bologna has four wins from six home games, and it should be too strong for Venezia.Atalanta vs. SpeziaAtalanta -1 (-150)The home side is surging with momentum and it should ease to victory against struggling Spezia.Atalanta vs. SpeziaJosip Ili?i? to Score (+110)The Slovenian striker has been prolific since returning from injury and should get plenty of chances.

SEE ALSO: All Soccer Picks and Predictions

Picks made on 11/18/21 at 7:15 a.m. ET.