Manchester United vs. Arsenal Matchday 6 Premier League Picks: Will the Gunners Maintain Perfect Start Against Resurgent Red Devils?

Arsenal are the only team in the Premier League with five wins in five games, while Manchester United have won their last three after opening the season with two defeats. Here are the insights for Manchester United-Arsenal on Matchday 6 of the Premier League.

Arsenal survived a scare from Aston Villa to maintain their 100% record, while Manchester United are up to fifth with maximum points from their last three games.

Here are our Manchester United-Arsenal Premier League picks for Matchday 6 (odds via DraftKings Sportsbook, PointsBet, and FanDuel Sportsbook; pick confidence based on a 1-to-5- star scale).

Manchester United vs. Arsenal Game Info

Date: Sunday, Sept. 4, 11:30 a.m. ET
TV: fuboTV, NBC Sports
Location: Old Trafford, Manchester, England
Weather: 68 degrees, 24% chance of precipitation, 10-mph winds

Manchester United vs. Arsenal Odds Analysis

Across our top-rated sportsbooks, Manchester United are actually the favorites, priced at +160 on FanDuel and DraftKings, and +155 on PointsBet due to their home-field advantage and current win streak.

Manchester United vs. Arsenal Picks

Manchester United vs. Arsenal ATS Pick

Arsenal -0.5 (+155) ★★★

While Arsenal have kept up their perfect campaign, thanks to resilient playmaking and attacking flair under Mikel Arteta, they can be vulnerable on defense, and have allowed teams back into games. 

Their last two matches have ended 2-1, against Fulham and Aston Villa, while Manchester United’s last two have been 1-0 road wins over Leicester and Southampton.

United may be on a three-game winning streak, but Arsenal have won three of the last five meetings against the Red Devils, their latest being a 3-1 victory in April.

The Gunners' ability to have multiple scorers will cause chaos even for the defensive likes of new United signings Casemiro and Lisandro Martinez. And, while United have scoring power in Bruno Fernandes and Jadon Sancho, their top scorer last season, Cristiano Ronaldo, is yet to find the net.

Arsenal’s schedule to start the season may have been softer than United, but the improvements they've made this transfer window gives them the edge on Sunday.

Manchester United vs. Arsenal O/U Pick

Over 3.5 (+176) ★★★★

These two clubs have produced more than 3.5 goals in each of their last two encounters, and while United have only scored twice or more in just one match so far, Arsenal have scored three or more goals twice this season.

As United become more comfortable offensively with players like Jadon Sancho netting twice already this season, Arsenal have multiple attackers such as Gabriel Jesus, Gabriel Martinelli, and Martin Odegaard.

With all three of those Gunners scoring at least three goals this season, and all three scoring 0.62 goals per 90 and sitting at a 1.5 or more expected goal rate, they will be looking to widen the gap between United further than the one spot they finished above them last season.

Manchester United vs. Arsenal Prop Pick

Bukayo Saka anytime scorer (+260) ★★★

With two assists so far, Bukayo Saka is close to getting back amongst the goals with ten shots (two on target) this season, including great opportunities against Aston Villa which saw him end the game with an expected goal rate of 0.5.

United know that Jesus, Odegaard and Martinelli are the players to watch for Arsenal, who have been able to score from set pieces, the counterattack and off the dribble downfield. But Saka is a creative midfielder, and a constant threat.

Taking advantage of a United backline that has conceded seven goals already, Saka is next in line to be on the Gunners' scoresheet, as his expected goal rate has risen to 1.0.

Where to Bet on Manchester United vs. Arsenal Picks

Here are our top-rated sportsbooks:

FanDuel Sportsbook
Caesars Sportsbook
DraftKings Sportsbook
PointsBet
BetMGM

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Manchester United-Arsenal picks made 9/2/2022 at 1 p.m. ET