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Champions League Odds & Best Bets This Week for Quarterfinals Second Leg

Anthony Wootton

Last Updated: April 19, 2023 8:41 AM EDT • 3 min read.

Karim Benzema of Real Madrid during La Liga Santader match between Real Madrid and Real Betis.
Karim Benzema of Real Madrid during La Liga Santader match between Real Madrid and Real Betis. Photo by DAX Images/NurPhoto.

Two games remain to be played in the second leg of the Champions League quarterfinals. Read on for our Champions League best bets for the quarterfinals' second leg based on the best Champions League odds.

Real Madrid and AC Milan are safely on to the semifinals of the Champions League. Man City, who play Bayern Munich for a second time on Wednesday, are also nearly assured a semifinal berth. Inter carries a 2-0 lead into its second quarterfinals match against Benfica.

Here are our Champions League best bets for the quarterfinals' second leg (odds via FanDuel Sportsbook and DraftKings Sportsbook); pick confidence based on a 1-to-5-star scale).

Champions League matches and odds

(Odds via DraftKings)

  • Bayern Munich (+170) vs. Man City (+145)
  • Inter (+110) vs. Benfica (+260)

Champions League best bets

  • Total: Bayern Munich vs. Manchester City Under 2.5 goals (+146 via FanDuel) ⭐⭐⭐
  • Prop: Inter vs. Benfica both teams to score no draw (+160 via DraftKings) ⭐⭐⭐⭐

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Top Champions League picks

Total: Bayern Munich vs. Manchester City Under 2.5 goals (+146 via FanDuel) ⭐⭐⭐

This tie is over as Man City sits comfortably atop the Champions League odds list. City head to Munich with a 3-0 lead, which is too big an advantage for the German giants to overcome. Only four teams in Champions League history have progressed from the knockout rounds after losing by three or more goals in the first leg. 

Manchester City have the highest pass completion rate under pressure of any team in this season’s competition (86.4%). Pep Guardiola’s side have also completed the highest number of passes under pressure this term (3,802 in nine matches). Expect them to maintain possession and force Bayern to chase the game. 

The Sky Blues have the lowest xGA of all the quarterfinalists (5.5). Bayern’s xG of 17.2 ranks in the bottom half of the last eight teams in the competition, therefore they’re going to find it difficult to score. Guardiola’s side have an FA Cup semi-final at the weekend, followed by a Premier League title clash with Arsenal next week. With a 3-0 advantage, he can afford to let his players take it easier than in recent matches.  

It could be a dull spectacle for the neutral, but we can cash in with the few chances created. 

Prop: Inter vs Benfica, both teams to score no draw (+160 via DraftKings) ⭐⭐⭐⭐

Benfica are currently unbeaten in seven away matches in the Champions League (four wins). This is their longest ever unbeaten run away from home in the competition. They have won their last two away matches and could win three in a row for the first time since March 1990. Only Manchester City and Napoli (25) have scored more goals than the Portuguese outfit (23) in the tournament this season. 

Benfica have already won away to Italian opposition in the current campaign, beating Juventus 2-1 during the group stages. 

Keep an eye on 21-year-old forward Gonçalo Ramos. He’s been directly involved in four goals in his last four Champions League appearances for Benfica (three goals and one assist). He’s also applied more pressures (674) and pressures in the final third (299) than any other striker in the competition this season.

Inter have the highest xGA (12.1) of all the teams competing in the quarterfinals. Although they did well to hold off Benfica in the first leg, the Portuguese giants must attack to make up the two-goal deficit. Inter are vulnerable at the back and I expect Benfica to score. 

The Italians have firepower too and could capitalize on Benfica being left exposed in defense as they chase the game. Romelu Lukaku has scored nine goals in 14 appearances for Inter in the Champions League, with only four players now scoring more goals for the club in the competition.

This could become an open game with goals from both sides. We don’t care who wins, so long as there’s a winner. Inter would settle for a draw, but Benfica’s attack is too much of a threat for them to sit on their aggregate lead. This tie works to our advantage for this play and is worthy of the four-star treatment. 

Champions League best bets made 04/17/2023 at 12:30 p.m. ET.

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Written By:
Anthony Wootton
Anthony is an accredited NFL journalist and has been reporting on the league for over a decade, covering the London games for the BBC and other broadcast outlets. He's presented a North American sports show for national radio across the UK, which is now the TransAtlantic Sports Show podcast. Anthony has also produced and presented radio documentaries on football for global audiences. He has years of betting experience, writing NFL tips for some of the industry's biggest sportsbooks. He's a producer of sports content, including Premier League, LaLiga, Bundesliga, Champions League, and international soccer. He's a keen follower of sport, and a long-time sufferer of English Championship team, Blackburn Rovers. He's a keen runner and completed a challenge of running every day in 2021, which included a minimum distance of 5km in the rules.