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FOXBOROUGH, MASSACHUSETTS - NOVEMBER 28: Mac Jones #10 of the New England Patriots passes the ball against the Tennessee Titans in the second quarter at Gillette Stadium on November 28, 2021 in Foxborough, Massachusetts. Adam Glanzman/Getty Images/AFP (Photo by Adam Glanzman / GETTY IMAGES NORTH AMERICA / Getty Images via AFP)

Check out all of our NFL picks and predictions for Week 13.

The Dallas Cowboys opened Week 13 with a 27-17 road win over the New Orleans Saints. Dallas covered the spread while the point total fell just shy of the 45.5-point closing line.

There are another 12 games on Sunday's schedule, with the New England Patriots and Buffalo Bills wrapping up the week on Monday Night Football.

Here are our against the spread and Over/Under NFL Week 13 picks (click each link for a full preview).

NFL Week 13 Picks

4 p.m. ET slate

Jacksonville Jaguars vs. Los Angeles Rams | Rams -12.5 | Over 47.5Jaguars: SU: 2-9 | ATS: 4-7 | O/U: 2-9Rams: SU: 7-4 | ATS: 4-7 | O/U: 6-4-1

Washington Football Team vs. Las Vegas Raiders | Washington +2.5 | Under 49.5Washington: SU: 5-6 | ATS: 4-7 | O/U: 5-6Raiders: SU: 6-5 | ATS: 5-6 | O/U: 6-5

Baltimore Ravens vs. Pittsburgh Steelers | Ravens -4 | Under 44Ravens: SU: 8-3 | ATS: 5-6| O/U: 5-6Steelers: SU: 5-5-1 | ATS: 4-7 | O/U: 4-6-1

San Francisco 49ers vs. Seattle Seahawks | Seahawks +3.5 | Under 4649ers: SU: 6-5 | ATS: 5-6 | O/U: 6-5Seahawks: SU: 3-8 | ATS: 5-6 | O/U: 1-9-1

SEE ALSO: Top Expert NFL Prop Picks for Week 13

Sunday Night Football

Denver Broncos vs. Kansas City Chiefs | Broncos +9.5 | Under 47.5Broncos: SU: 6-5 | ATS: 6-5 | O/U: 2-9Chiefs: SU: 7-4 | ATS: 4-7 | O/U: 5-6

SEE ALSO: Top Expert Betting Picks for Week 13

Monday Night Football

New England Patriots vs. Buffalo Bills | Patriots +3 | Over 42Patriots: SU: 8-4 | ATS: 8-4 | O/U: 6-6Bills: SU: 7-4 | ATS: 6-4-1 | O/U: 5-6

SEE ALSO: All picks and odds. Be sure to check out SportsbookReview.com’s community forums and betting tools.