Arizona Cardinals vs San Francisco 49ers Preview: NFL Week 5 Picks

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Tuesday, October 4, 2016 9:59 PM

The Arizona Cardinals have struggled mightily this season, with three straight up losses so far as a favorite of more than a field goal. In NFL Week 5 on Thursday night football, though, they will once again be a favorite of more than a field goal, this time on the road against the San Francisco 49ers, who have also been overvalued ATS so far this season. Professional handicapper Doug Upstone breaks down the Arizona Cardinals vs San Francisco 49ers game and gives a free pick with SBR Videos hosts Mike Brenner and Peter Loshak.

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