NFL Picks: Game-by-Game ML Predictions for All Week 1 Games

Nikki Adams

Wednesday, September 9, 2015 1:30 PM UTC

Wednesday, Sep. 9, 2015 1:30 PM UTC

We look at the winners markets for each and every game in week 1 NFL betting. Find out which teams we are backing for the ‘W’ on our NFL picks.

Steelers+235 vs. Patriots -280
The Steelers come into this game a bit banged up and short on key players due to suspensions. The Patriots come into this game with a chip on their shoulders, none bigger than the one on Tom Brady’s shoulder. Deep into the season, this game might have been a bit more of a tossup with both teams rounded out into form. As it is, with it taking place at Gillette Stadium; a home opener for the defending champions; a vindicated Tom Brady calling the shots…do you really want to bet against the Patriots?
NFL Picks: Patriots -280 at William Hill


Panthers -170 vs. Jaguars +150
The Jaguars appear to be headed in the right direction and they could be on their way to a much better season, but an opening game against Cam Newton and the Panthers, defending NFC South champions and last year’s playoffs contender, is a tough ask for a restructuring outfit. As tempting as the potential upset is on the NFL betting floor, we’re sticking with the NFL odds and backing the road faves in a narrow win.
NFL Picks: Panthers -170 at Bet365


Browns +145 vs. Jets -175
The Cleveland Browns head to NY as the road underdogs, which is the correct outlook in our opinion. The Jets aren’t without injury woes from the preseason by Ryan Fitzpatrick is a capable veteran and he seems to be taking to the starting role admirably. Jets at home as the -175 favourites is our recommended NFL pick.
NFL Picks: Jets -175 at Heritage


Packers -290 vs. Bears +235
It’s obvious that odds makers aren’t buying what the Chicago Bears are selling, sending them into their home opener as the massive +235 underdogs. A lot of that absorbing price though is down to the quality of the Packers and their impressive record against the Bears, which stands 9-1 SU in their last ten games.
NFL Picks: Packers -290 at 5Dimes


Colts -145 vs. Bill +125
The Indianapolis Colts are amongst the Super Bowl favourites across sports betting platforms, prompting favourable NFL odds for their season opener on the road in Buffalo. However, we think the Bills are better than the odds makers would have you believe. Granted Tyrod Taylor beating Andrew Luck sounds improbable, if you think of the game in such confined parameters. Bills defense though to give Luck something to think about, even give him a few headaches. Now that might not be so improbable.
NFL Picks: Bills +125 at BetCris


Chiefs +105 vs. Texans -115
If the Chiefs are as good as their preseason account, they should win this game handily. Alex Smith and his O-line were sharp and he finally seems to have some solid weapons to throw to, which adds such more dimension to their game. That said, it’s not surprising that the Texans are home favourites on the NFL odds board with home advantage over the Chiefs and their stout defense. But it’s a tight NFL betting line for a game that could go either way. This one is a right tossup on our NFL picks. We’re going with the Chiefs at +105 on our NFL picks, with the caveat being that we won’t be surprised if the Texans do come away winners at home.
NFL Picks: Chiefs +105 at JustBet


Dolphins -192 vs. Redskins +165
The Miami Dolphins descend on the Washington Redskins as the road favourites and they are sure to be a popular NFL pick to win outright. On one hand, the Dolphins do appear to be headed in the right direction. On paper, they are much improved from last season. But can they be really trusted to deliver in week 1 NFL betting on the road? The fact that odds makers aren’t putting much stock in the Redskins might suggest the Dolphins can be trusted to deliver on their favourable NFL odds. We’re of a mind to go against the grain and back the Redskins.
NFL Picks: Redskins +165 at Island Casino


Seahawks -200 vs. Rams +170
The Rams are huge underdogs on the NFL odds board in their home opener against the Seattle Seahawks for good reason. However, they played their cards close during the preseason, which could mean they have a few tricks up their sleeve. Does that mean we might be treated to a first week shocker here? All things being considered, it’s unlikely but not impossible. Meaning worth a tickle at +170 NFL odds, if you are so brave. Just don’t bet the farm on it.
NFL Picks: Rams +170 at TheGreek


Lions +130 vs. Chargers -155
It’s somewhat surprising that the NFL odds for this game are quite so contrasting. Given the calibre of both quarterbacks and the respective depth of each team, this game should have benefited from a much tighter betting NFL line, As a result, we’re of a mind to go against the odds makers here. Lions at +130 NFL odds is too tempting to ignore.
NFL Picks: Lions +130 at Bookmaker


Saints +115 vs. Cardinals -135
Drew Brees and the Saints O-line make a strong case for the win, but the Saints defense is sorely lacking. By virtue of that weakness, it’s impossible to predict a road upset in Arizona.
NFL Picks: Cardinals -135


Ravens +180 vs. Broncos -220
This is going to be one of the must-see games in week 1 NFL betting. Peyton Manning and the Broncos look to open the season at Mile High with a significant win over last season’s impressive-playoffs contenders, the Baltimore Ravens. This is going to be a gauntlet throwing win in the AFC for either side. One has to give the edge to the Broncos on account of solid home form, including last season’s 8-0 SU record.
NFL Picks: Broncos -220 at 5Dimes


Bengals -175 vs. Raiders +115
Cincinnati Bengals, typically, can be trusted to beat lesser teams in the NFL. Raiders are improving, but not until they finish a season with a winning record can they deservedly be dubbed a good team. Based on past performances, this is a game the Bengals should clinch.
NFL Picks: Bengals -175 at SIA


Titans +140 vs. Bucs -160
The Tampa Bay Buccaneers are expected to be much improved this season, but they’re faced with the pressure of winning their first regular home season game in two years in week 1 NFL betting. Fortunately, they could have faced a much tougher task than the Titans, which has us mildly hopeful for the home win.
NFL Picks: Bucs -160 at Bet365


Giants +210 vs. Cowboys -250
This is a tougher game to call in our books than the odds makers would have you believe in week 1 NFL betting. Giants have disappointed in the last few seasons, hence their rather large NFL odds to win outright on the road at +210. The Cowboys were a standout team last season, but on the road where they went undefeated 8-0. At home, they were fallible, which makes us question their pricey -250 NFL odds. But does that mean the Giants at +210 are the smart NFL pick over the overpriced Cowboys at -250 NFL odds?  It’s a long shot. But fortune favours the brave, so they say.
NFL Picks: Giants +210 at JustBet


Eagles -155 vs. Falcons +135
If the Philadelphia Eagles are anywhere as good as they were in the preseason, watch out. Falcons have made some improvements that augur well for their season. Importantly, they have the offense to make this one of the first week’s thrilling showdowns. But we’re with the bookies here and taking the Eagles to win outright at -155 NFL odds.
NFL Picks: Eagles -155 at Bet365


Vikings -140 vs. 49ers +120
Everybody is crushing on the Minnesota Vikings after a solid preseason account in which they appeared to be sporting midseason form. Similarly, everybody has gone off the Niners since their fall from grace last season. This is a Monday Night Football game and a road game for the Vikings, which means pressure. Not to mention the weight of expectation as road favourites might play havoc with second year quarterback Teddy Bridgewater’s focus. Make no mistake, the Vikings are on the up, but how prepared are you to put down good money on a road win in week 1 at the Levi Stadium?
NFL Picks: 49ers +120 at Pinnacle

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