No quarterback suffered a major injury in Week 11 so that's a positive. Probably no team enters Week 12 with more injury questions than the Denver Broncos. Here's a look at all injuries that could alter NFL betting lines this week.
Montee Ball, RB, Emmanuel Sanders, WR, & Julius Thomas, TE, Broncos
Denver suffered perhaps the biggest upset of the 2014 season on Sunday in falling 22-7 in St. Louis. The Broncos are no longer alone atop Bovada's NFL odds to win the Super Bowl. It's now a three-way tie at +450 along with New England and Green Bay. The Pats have become AFC favorites at +180 with Denver at +220. The Broncos opened as 7-point favorites on sportsbooks for this Sunday's home game with Miami. Ball just returned from a groin injury but re-aggravated it in the loss and will miss 2-3 weeks. Thomas suffered an ankle injury and is likely to have to miss at least one game. Sanders suffered a concussion vs. the Rams and thus must pass all the NFL protocols this week to face Miami. Those three players have combined for 20 touchdowns.
Adrian Peterson, RB, Vikings
Peterson isn't hurt but it now seems pretty clear that he won't be playing in the NFL this season and probably not ever again for the Minnesota Vikings. The NFL finally decided its punishment on Peterson as he was suspended the rest of this season -- at least -- without out pay. The league won't even consider his reinstatement until April 15, 2015. Peterson was indicted in September on a felony charge of injury to a child, but he pleaded no contest to a lesser charge of misdemeanor reckless assault. The Vikings can now officially move on. They are 9-point underdogs on NFL odds this week at home vs. Green bay.
Reggie Bush, RB, Lions
Bush sat out Detroit's Week 11 loss in Arizona due to an ankle injury, his third game missed this season. However, Detroit expects Bush to play Sunday at scorching-hot New England. The nagging ankle injury has sidelined Bush every other game the past six weeks. The Lions are 31st in the NFL in rushing and they are going to want to chew up clock this week to keep Tom Brady off the field. The Patriots opened as 7-point favorites at sportsbooks.
Giovani Bernard, RB, Bengals
Bernard has missed the past three games with hip and collarbone injuries but is looking like a decent bet to play this week at Houston, Game No. 2 of the Bengals' three-game road trip. Bernard may want to hurry because rookie Jeremy Hill might take his job. Hill has had two games of at least 150 yards rushing with Bernard out. Cincinnati opened as a 1-point dog on NFL odds for Sunday's game.
Ahmad Bradshaw, RB, Colts
Crushing loss for Indianapolis. The Colts not only were blown out in Week 11 by New England, which could cost the team a crucial tiebreaker in the AFC playoff seedings, but they also lost Bradshaw to a season-ending broken ankle. Bradshaw leads the Colts with 425 yards rushing and has eight touchdowns (two rushing, six receiving; the NFL record for TD catches by a running back in a season is nine). That puts all the pressure on Trent Richardson, who has never lived up to expectations in the NFL. The Colts already have said they aren't interested in former Raven Ray Rice even if Rice is reinstated by the NFL. Indy is the biggest Week 12 favorite at sportsbooks at -13.5 vs. Jacksonville.
Brandin Cooks, WR, Saints
Cooks was one of the preseason betting favorites to win NFL Offensive Rookie of the Year, but you can forget about that now as Cooks will miss 4-6 weeks following thumb surgery. Cooks, one of the NFL's fastest players, had become a trusted target of Drew Brees as Cooks had 53 catches for 550 yards and three touchdowns.
Karlos Dansby & Jabaal Sheard, LBs, Browns
Cleveland got caught in a trap game in Week 11, falling 23-7 at home to Houston. To make matters worse, the defense lost two key contributors for significant time. Dansby, who was playing at a Pro Bowl level, could miss a month and Sheard the season. Prior to being hurt with eight minutes left in the second quarter Sunday, Dansby had missed just four of 641 plays this year. He had 73 tackles and three sacks. Sheard, more of a situational pass rusher, had 36 tackles and two sacks. Cleveland is +3 on NFL odds this week at Atlanta. There is some good news for the Browns: star receiver Josh Gordon is now eligible off suspension and will play.