Skip to main content
Head coach Robert Saleh of the New York Jets reacts during the game against the Baltimore Ravens at MetLife Stadium on September 11, 2022.
Head coach Robert Saleh of the New York Jets reacts during the game against the Baltimore Ravens at MetLife Stadium on September 11, 2022. Photo by Mike Stobe/Getty Images via AFP.

Several marquee matchups highlight the second week in the NFL which is great for the prop market. Here are our best game props for Week 2.

Prop betting gives bettors so many fun and creative ways to enjoy a weekend of football. This week gives us 13 Sunday matchups as well as two Monday night contests. While it’s still fun to bet on the typical passing and rushing props, digging a little deeper you'll find even more creative ways to bet on games.

Here are our best NFL game props of Week 2 (odds via DraftKings Sportsbook).

Top Game Props for Week 2

(All props via DraftKings and include only Sunday games.)

  • Justin Jefferson & A.J. Brown: 300+ receiving yards & 2+ TDs combined (+1600)
  • Most points scored by any team Over 41.5 (+100)
  • New York Jets lowest-scoring team (+750)

Week 2 Game Prop Specials

Jefferson & Brown: 300+ receiving yards & 2+ TDs (+1600)

Wide receiver Justin Jefferson opened his third season with the Minnesota Vikings by catching nine passes for 184 yards and two touchdowns. The young wideout has topped the 100-yard mark 15 times in his career. He has eclipsed 150 receiving yards now five times in that span. Last week, he caught two touchdown passes. Last season, he had 10 scoring receptions.

In his Philadelphia Eagles debut, A.J. Brown garnered a team-high 13 targets. He caught 10 of them for 155 yards. The pass catcher with the next highest reception total was tight end Dallas Goedert, who caught three of his four targets for 60 yards. Brown will be tested more this week against a Vikings defense that allowed Green Bay Packers Aaron Rodgers to throw for only 195 yards. However, Brown's Philadelphia’s best weapon and will see enough volume to hold up his end of this prop.

  Check out the latest comprehensive and most trusted Sportsbook Reviews by SBR.

Most points scored by any team Over 41.5 (+100)

In Week 1, the Kansas City Chiefs topped this mark by scoring 44 points against the Arizona Cardinals. Last season, only seven weeks failed to yield a team that scored at least 42 points. Four of those weeks had teams score exactly 41 points in their games.

The game total for the Week 2 contest between the Cardinals and Las Vegas Raiders is 51.5. This holds the possibility of one of these teams breaching this prop mark. 

Another game with a favorable predicted total is the Washington Commanders and the Detroit Lions which is set at 48.5 points. Last week, Detroit scored 35 points against the Eagles.

Jets to be lowest scoring team (+750)

New York Jets QB Joe Flacco threw for 309 yards last week, but the Jets managed only nine points against the Baltimore Ravens. Surprisingly, they were not the lowest scoring team of the week, but they did land fourth in that list.

Where to Bet on NFL Prop Picks

Here are our top-rated sportsbooks:

SEE ALSO: All picksodds, and sports betting news. Be sure to check out SportsbookReview.com’s community forums and betting tools.

NFL game prop picks made on 9/15/2022 at 7:37 p.m. ET.