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Quarterback Justin Herbert of the Los Angeles Chargers celebrates while leaving the field following his team's win over the Washington Commanders, and we offer our top player props for Patriots vs. Chargers based on the best NFL odds.
Quarterback Justin Herbert of the Los Angeles Chargers celebrates while leaving the field following his team's win over the Washington Commanders. Photo by Rob Carr/Getty Images via AFP.

The Houston Texans are 0-2-1 but its the Los Angeles Chargers most in need of a bounce-back win after their humbling 38-10 loss last week. Let's check out our top Chargers-Texans picks for Week 4.

Battling numerous injuries, including QB Justin Herbert being far from at full health, the Chargers suffered a 38-10 loss to the Jacksonville Jaguars on their home field last week. That followed a disappointing 27-24 loss to the Kansas City Chiefs on Thursday Night Football, in which Herbert first suffered the injury.

The Texans drew a surprising tie with the Indianapolis Colts in Week 1 but then took back-to-back losses at the hands of the Denver Broncos and Chicago Bears. However, Houston is still 2-0-1 against the spread.

Check out our top NFL Week 4 picks here.

Here are our top Chargers-Texans NFL picks for Week 4 (odds via DraftKings Sportsbook and FanDuel Sportsbook; Pick confidence is based on a 1-to-5-star scale).

Chargers vs. Texans Game Info

Date: Sunday, Oct. 2, 1 p.m. ET
TV: CBS
Location: NRG Stadium, Houston, TX
Weather: 88 degrees, 3% chance of precipitation, 7-mph winds

Chargers vs. Texans Odds

Chargers vs. Texans Odds Analysis

Despite 67% of the tickets and 63% of the handle backing Los Angeles, the spread has fallen from Chargers -7 to a consensus line of -6 as of Sunday morning.

The Over/Under has dropped from 46 to 45. Bettors are more split on these numbers with 56% of the tickets on the Over accounting for just 38% of the handle.

Chargers vs. Texans Picks

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Chargers vs. Texans ATS Pick

Texans ML (+215) ★★★★

The thought of the Texans beating the Chargers may seem laughable at first, but there’s some betting value to be found if you consider the context. There have already been several upsets in 2022, and another one could be coming due to the number of injuries Los Angeles is dealing with.

Left tackle Rashawn Slater is out for the year, and superstar edge rusher Joey Bosa also won't suit up in Week 4. To top it all off, quarterback Justin Herbert is still battling a rib injury, and wideout Keenan Allen was limited in practice on Wednesday and Thursday.

The Texans upset the Chargers in Week 15 last season, and that could very well happen again.

Chargers vs. Texans O/U Pick

Under 45 (-106) ★★★★★

This total appears a bit high given the number of injuries to consider, especially on the Chargers’ side. Additionally, the Texans haven’t really been in high-scoring games this campaign. Houston hasn't allowed more than 23 points, but the team also hasn't scored 20-plus points.

Combine that with the Herbert-Allen combo likely not being at its usual high-flying level, and a lower point total becomes a logical result.

Chargers vs. Texans Prop Pick

Ekeler Over 56.5 rushing yards (-115) ★★★★★

It’s been a frustrating season so far full of poor rushing efficiency and underuse for Chargers running back Austin Ekeler, who's coming off an incredible 2021-22 campaign. He rushed 14 times in back-to-back weeks to start the year, before only running four times for five yards in Week 3. 

His passing-game usage is still high-volume, but the lack of rushing is puzzling. However, Ekeler is too talented to stay down for long, and he's in a good spot for a breakout game. Herbert will likely be handing the ball off more than usual due to the significant injuries along the Chargers' offensive line, and Ekeler won't take that opportunity for granted.

Where to Bet on Chargers-Texans Picks

FanDuel Sportsbook
Caesars Sportsbook
DraftKings Sportsbook
PointsBet
BetMGM

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Chargers-Texans picks made 9/30/2022 at 2:39 p.m. ET.