Cardinals vs. Bills NFL Player Props, Odds
Two of the NFL's most exciting quarterbacks square off in Week 1 when Josh Allen and Kyler Murray take the stage Sunday at 1 p.m. ET, as we offer our best Cardinals vs. Bills player props.
Buffalo is out to prove it's still a Super Bowl odds contender after coming up four points short of playing in the AFC championship last year. Arizona finished dead last in the NFC West with a 4-13 record but would love to turn that around with a win in Week 1.
Cardinals vs. Bills player props: Sunday
Odds as of Friday and subject to change.
- Kyler Murray Under 33.5 pass attempts (-115 via Hard Rock Bet) ⭐⭐⭐⭐
- Curtis Samuel 50+ receiving yards (+320 via DraftKings) ⭐⭐⭐⭐
- Kyzir White Over 8.5 tackles + assists (-105 via BetMGM) ⭐⭐⭐⭐
NFL picks made Friday; odds subject to change.
Kyler Murray Under 33.5 pass attempts (-115) ⭐⭐⭐⭐
The consensus number for Murray's pass attempts is 33.5, which can be found across many of our best sportsbooks. One exception is FanDuel, which is adding one more attempt to the total, offering 34.5 at -122 for the Under.
The Cardinals signal-caller appeared in eight games last season and averaged exactly 33.5 pass attempts per game, clearing this mark in just three of them. Over the course of his career, Murray slightly improves to 34.5 pass attempts per game.
Arizona is facing a Buffalo defense that allowed the seventh-fewest pass attempts per game to opposing quarterbacks last season. The opposition put the ball in air 32.3 times on average last year, and that number dipped to 31.8 at home.
Best odds: -115 via Hard Rock Bet | Implied probability: 53.49%
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Curtis Samuel 50+ receiving yards (+320) ⭐⭐⭐⭐
Most of our best sports betting sites have projected Samuel for 27.5 receiving yards in his first game with the Bills. However, this total feels quite low considering his potential to become a top receiving target in Buffalo.
For this reason, I suggest you climb the ladder to secure a better number. Both DraftKings and bet365 are offering the best value on this wager, which would pay out $32 in profit on a $10 stake.
Two of the Bills’ top pass-catchers have left Buffalo with Stefon Diggs joining the Texans and Gabe Davis now in Jacksonville.
Samuel’s arrival to the team pairs him with two breakout stars from last season, wideout Khalil Shakir and tight end Dalton Kincaid, who combined for 118 receptions and 1,419 receiving yards last year.
Last season, Samuel appeared in 16 games with the Washington Commanders and crossed the 50-yard threshold in six of those games as the No. 2 option behind Terry McLaurin.
Best odds: +320 via DraftKings | Implied probability: 23.81%
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Kyzir White Over 8.5 tackles + assists (-105) ⭐⭐⭐⭐
The line for White is consistent across the board projecting him at 8.5 tackles and assists on almost all of our best sports betting apps. DraftKings and bet365 have this slightly juiced at -110 for the Over, while BetMGM and Hard Rock offer a small discount.
White will have plenty of opportunity to best this mark given the Bills registered the third-most rushing attempts (30.8) in the league last season. That was even with Diggs and Davis at wide receiver, and both are no longer in Buffalo - leaving Samuel, Shakir, and Mack Hollins as the main wideouts.
I expect the Bills to lean on James Cook and the run game quite a bit to open the season. Last year, White averaged 8.2 total tackles in his 11 games. He cleared this prop mark in five of those games.
Best odds: -105 via BetMGM | Implied probability: 51.22%
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Cardinals vs. Bills odds
See all of this week's NFL odds and NFL scores.
Cardinals vs. Bills game info
- When: Sunday, Sept. 8
- Kickoff: 1 p.m. ET
- Where: Highmark Stadium (Orchard Park, N.Y.)
- How to watch: CBS/Paramount+
- Weather: 63 degrees, 4% chance of precipitation, 10-mph winds
- Favorite: Bills (-110 via Caesars)
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