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Justin Fields of the Chicago Bears drops back to pass during a game against the Green Bay Packers, and we offer new U.S. bettors our exclusive Caesars promo code.
Justin Fields of the Chicago Bears drops back to pass during a game against the Green Bay Packers. Photo by Stacy Revere/Getty Images via AFP.

There was no shortage of drama during NFL Week 3 action, as a couple of the league’s best teams lost in heartbreaking fashion. Here are our best moneyline bets for NFL Week 4.

Those who pursued the underdog while placing NFL Week 3 moneyline bets were generally rewarded, thanks to some shocking upsets including the Indianapolis Colts' 20-17 win over the Kansas City Chiefs. Will going against the grain continue to pay off in Week 4?

Here are our top moneyline picks for the NFL's Week 4 (odds via Caesars Sportsbook and BetRivers).

NFL Week 4 Moneyline Picks

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Ravens-Bills ML Pick

Ravens (+160) ★★★★

Baltimore Ravens quarterback Lamar Jackson continues to make his case for MVP, throwing four passing touchdowns and running in a fifth during last week’s bounce back win against the New England Patriots. The offense is averaging 33.0 points per game, and could become even more high-octane as talented running back J.K. Dobbins works his way back from a lengthy injury absence.

The Buffalo Bills were flying high after the first two weeks, but Week 3 saw them stifled by the Miami Dolphins. Bills quarterback Josh Allen threw for 400 yards on 63 pass attempts, but only managed to find the end zone twice. Although Buffalo remains a powerhouse, it’s surprising to see Baltimore listed as an overwhelming underdog. This will be a close game, and there’s a lot of value in wagering on the Ravens at these odds.

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Bears-Giants ML Pick

Bears (+158) ★★★★★

It’s been a strange and underwhelming season for the 2-1 Chicago Bears, who boast a deceivingly good record thanks in large part to their pair of star running backs. In fact, the Bears are the first team in over a decade to have fewer than 10 pass completions in each of their first three games. In essence, the Bears' success is predicated on how well their run game is executing.

Luckily, they draw a favorable matchup against the New York Giants in Week 4. The Giants just allowed the Dallas Cowboys to rush for 176 yards and a touchdown in Week 3, and also gave up over 146 rushing yards to the Carolina Panthers in Week 2. They’ve also failed to score very much, averaging only 18.7 points per game through three games. If Chicago’s run game stays hot, New York will get cooked.

Titans-Colts ML Pick

Titans (+150) ★★★★

The AFC South hasn’t exactly been filled with powerhouse teams and marquee matchups in recent years, but the Tennessee Titans and the Indianapolis Colts also both have a superstar running back that could legitimately be the best in the NFL. The Colts’ aforementioned victory over the Chiefs in Week 3 certainly gave that roster a boost, but they’ve still managed to score only 40 total points through three games.

Fortunately for the Colts, the Titans are tied for third last in points allowed this season with 84. Still, there’s a path for Tennessee to win this game despite being the underdog. Prior to Week 3, Indianapolis was shut out by the Jacksonville Jaguars and struggled in a tie against the Houston Texans. This game will be close, but the Titans’ chances of winning are better than the odds imply.

Where to Bet on NFL Moneyline Picks

Here are our top-rated sportsbooks:

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Week 4 NFL moneyline picks made 9/27/2022 at 3:20 p.m. ET.