Who do we think will make a run into the Final Four? Check out our picks, along with the associated college basketball betting odds attached to each team.
Florida Gators (+525)
The overall favorite on the board right now is the Gators, who come in as the top overall rank in the NCAA tournament fresh off an undefeated run in SEC play.
Florida hasn't lost since December 2nd, having reeled off 26 straight wins ahead of their first round clash against the winner of Albany and Mount St. Mary's. Victories over ranked opponents came against Kansas, Memphis and Kentucky (on three occasions).
The Gators have been so dominant because of their top-notch defense, which not only ranks first in the SEC but is up in the third spot within the entire country. They've allowed 57.9 points per game on 39.9 percent shooting overall.
Led by a point guard in Scottie Wilbekin that knows what he's doing and a host of other key players like Casey Prather, Michael Frazier II, Patrick Young and Dorian Finney-Smith, this team is ready for a deep run. Will they get your backing with your college basketball picks?
Michigan State Spartans (+550)
Despite shockingly being announced as a four seed, the Spartans are second on the futures list to emerge as national champions.
There's arguably no team playing better basketball than Michigan State right now. They just dominated the Big Ten tournament in style, beating Northwestern, Wisconsin and then Michigan all by double digits.
It wasn't exactly the kind of regular season many Spartans fans were expecting, but injuries really hampered this team's ability to fulfill their true potential. Everyone is back and healthy now though and we're beginning to see the Michigan State we all expected to see.
The Spartans are led by future NBA pro Gary Harris, but Adreian Payne, Keith Appling, Branden Dawson and Denzel Valentine have all been instrumental to the team's success this season. Michigan State should go far.
Louisville Cardinals (+575)
Another four seed makes the cut and that's the defending champion Cardinals.
Louisville has been a force to be reckoned with since a loss at Memphis earlier this month. They've won five straight and all five of those victories came in dominant fashion. Rick Pitino's crew totally dominated the AAC tournament, steamrolling through Rutgers, Houston and then Connecticut in the title game.
The Cardinals, of course, have the necessary experience to make another serious run at the national championship. What's more, their offense has been incredibly efficient throughout the season, with the team averaging 82.1 points per game thus far.
The main man to watch is Russ Smith, who returned for his senior year in hopes to repeat as national champs. He's joined by talented sophomore Montrezl Harrell, juniors Chris Jones and Wayne Blackshear and fellow senior Luke Hancock as the main contributors for a team ready to do damage.
Arizona Wildcats (+700)
Though sportsbooks aren't giving the Wildcats a ton of love on the betting odds board, they shouldn't be taken lightly whatsoever. They did enough to earn the number one seed in the West region, which features the likes of Wisconsin, Creighton and San Diego State.
It's not going to be an easy ride, but Arizona has fought through adversity before and will like their chances of doing it again.
The Wildcats lost in the Pac 12 title game to UCLA, but we shouldn't forget all the good things this team did throughout the year. Brandon Ashley, a key hog on both ends of the floor, was lost for the season, yet Arizona still managed to maintain their elite status.
The main offensive responsibilities will fall on Nick Johnson, along with fab freshman Aaron Gordon and big man Kaleb Tarczewski. T.J. McConnell is a savvy point guard who knows how to lead, while freshman Rondae Hollis-Jefferson has elevated his play in Ashley's absence.