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DeMar DeRozan and Goran Dragic of the Chicago Bulls celebrate a basket against the Toronto Raptors during the first half at United Center.
DeMar DeRozan and Goran Dragic of the Chicago Bulls celebrate a basket against the Toronto Raptors during the first half at United Center. Photo by Michael Reaves/Getty Images/AFP.

The Boston Celtics have won nine straight games. They'll visit the Chicago Bulls on Monday, who have lost four consecutive contests. Read on for our top Celtics-Bulls picks.

This matchup is about two teams heading in opposite directions. The Bulls have lost four games in a row, and only two of those were single-digit defeats. The Celtics have won nine straight, including four double-digit victories.

This is the third meeting between these two teams, with both squads winning at home. The Bulls are 2-0 against the spread in their meetings with Boston this season.

Here are our Celtics-Bulls NBA picks for Monday (odds via PointsBet and BetMGM; Pick confidence is based on a 1-to-5-star scale).

Celtics vs. Bulls Game Info

Date: Monday, Nov. 21, 8 p.m. ET
TV: NBC Chicago
Location: United Center, Chicago, IL

Celtics vs. Bulls Odds

Celtics vs. Bulls Odds Analysis

The Celtics opened as 5.5-point favorites, and the line moved to -6 quickly. The Celtics are drawing 76% of the cash and 72% of the tickets.

As for the total, the line opened at 226, and it's moved to 227.5. Bettors were backing the Over until it went up to 227.5. Now there's two-way action, with 77% of the cash on the Over and 56% on the Under.

Celtics vs. Bulls Picks

Celtics vs. Bulls ATS Pick

Bulls +6.5 (-115) ★★★

DeMar DeRozan is averaging over 35 points per game against the Celtics this campaign. He's been a key reason why the Bulls are enjoying so much success against Boston.

However, the true difference-maker on Monday should be Zach Lavine. He has yet to score 20 points against the Celtics, though Lavine has reached that plateau in eight of his other 10 games in 2022-23. He’s coming off one of the worst shooting performances of his career against the Orlando Magic, which significantly contributed to the Bulls' one-point loss.

Chicago will struggle to keep both Jayson Tatum and Jaylen Brown under control, but the team boasts enough weapons offensively to at least keep this one close.

Celtics vs. Bulls O/U Pick 

Over 227.5 (-107) ★★★

The Celtics have scored fewer than 110 points just once during their winning streak. The streak started with a 123-119 triumph over the Bulls, and that type of offense has been the norm for the Celtics. They're averaging 123.3 points over their last nine games while giving up over 100-plus points in every contest.

The Bulls are averaging just 107.8 points per game during their four-game losing streak. That average would be more than enough to cash the Over on Monday. Especially since Chicago is also allowing 118.3 points per game during its losing stretch.

Celtics vs. Bulls Prop Pick

DeRozan Over 23.5 (-120) ★★★★

DeMar DeRozan scored 46 points the last time these teams met. He went 13-for-23 shooting from the field and 20-for-22 from the free-throw line. Only Nikola Vucevic also scored more than 20 points for the Bulls in that game. 

DeRozan also scored 25 points during the first meeting between these two teams in 2022-23. He's registered 41, 28, 16, and 33 points during the club's four-game losing streak.

The Bulls will be leaning on him to pull off the upset over the Celtics. This line should really be closer to 25.5.

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Celtics-Bulls picks made 11/21/2022 at 8:58 a.m. ET