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VANCOUVER, BRITISH COLUMBIA - OCTOBER 16: Quarterback Nathan Rourke #12 of the BC Lions scrambles while being pressured by Shawn Lemon #40 of the Calgary Stampeders during the second half of CFL football action at BC Place on October 16, 2021 in Vancouver, British Columbia, Canada. Rich Lam/Getty Images/AFP (Photo by Rich Lam / GETTY IMAGES NORTH AMERICA / Getty Images via AFP)

Two of the better teams in the league, the 6-1 BC Lions and the 5-2 Calgary Stampeders, meet in a Week 10 CFL showdown. See who we like with our Lions-Stampeders picks.

The Lions have lost only one game this year and that was to the league-leading Winnipeg Blue Bombers in Week 5. They are 2-0 against the spread on the road. Meanwhile, the Stampeders are 0-3 against the spread at home. 

Here are our Lions-Stampeders CFL picks for Week 10 (odds via DraftKings Sportsbook).

Lions vs. Stampeders Game Info

Date: Saturday, Aug. 13, 7 p.m. ET
Location: McMahon Stadium, Calgary, AB
Weather: 80 degrees, 15% chance of precipitation, 12-mph winds

Lions vs. Stampeders Odds Analysis

The Lions opened as favorites at -120 on the moneyline. The line has flipped and now lists BC as an even-money underdog with a 1-point spread. Seventy percent of the cash is backing the Stampeders.

The total opened at 53.5 and has gone up by half a point in some spots. Most books have the game total at 53.5 at -110 odds.

Lions vs. Stampeders Picks

Lions vs. Stampeders ML Pick

Lions (-130)

The Lions have been on fire and are dominating in most statistical categories this season. Prior to the Blue Bombers game on Thursday against the Montreal Alouettes, Lions QB Nathan Rourke was leading the league in passing; his 21 passing TDs still lead the league.

With both teams missing their starting running back for Saturday's matchup, as James Butler (ankle, ribs) is questionable and Ka’Deem Carey (hamstring) was ruled out, the passing game should have an even bigger impact. Stamps QB Bo Levi Mitchell has only passed for seven touchdowns through seven games. The Lions should be able to easily control the game through the air.

Lions vs. Stampeders ATS Pick

Lions -2.5 (-110)

It’s expected that David Mackie will fill in for the Lions at running back. He hasn’t had many opportunities this year with how well Butler has played but does have a respectable 5.5 yards per carry. Also, look for Rourke to scramble as he’s racked up 233 rushing yards this year with a 7.3 yard per carry average.

Dedrick Mills and Peyton Logan will try and pick up the slack for the Stampeders with Carey out, however, the Lions’ pass game has far exceeded the Stampeders and they should pull ahead easily.

Lions vs. Stampeders O/U Pick

Under 53.5 (-110)

Without the balance provided by the regular starting running backs for these teams, I expect points to be at a premium in this Week 10 matchup. The high points total seems to be too much and I like the Under. While the Lions should have no trouble scoring, the Stampeders could have more trouble moving the ball against a stiff defense. Especially given that they are missing their top receiving option in Malik Henry as well as their fifth receiving option in Carey.

Where to Bet on Lions-Stampeders Picks

Here are our top-rated sportsbooks:

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Lions-Stampeders picks made 8/12/2022 at 7:50 p.m. ET