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VANCOUVER, BRITISH COLUMBIA - OCTOBER 16: Quarterback Nathan Rourke #12 of the BC Lions scrambles while being pressured by Shawn Lemon #40 of the Calgary Stampeders during the second half of CFL football action at BC Place on October 16, 2021 in Vancouver, British Columbia, Canada. Rich Lam/Getty Images/AFP (Photo by Rich Lam / GETTY IMAGES NORTH AMERICA / Getty Images via AFP)

The two teams yet to play multiple games face off, and one will start the season 2-0. See who we favor in our Argonauts-Lions picks.

Both the Toronto Argonauts and BC Lions have looked impressive after playing one game.  However, no team started better than the Lions, who scored a season-high 59 points. Meanwhile, Toronto squeaked past Montreal 20-19 in Week 2.  

Here are our Argonauts-Lions CFL picks for Week 3 (odds via DraftKings Sportsbook; Pick confidence is based on a 1-to-5-star scale).

Argonauts vs. Lions Game Info

Date: Saturday, June 25, 10 p.m. ETTV: ESPN+/TSNLocation: BC Place, Vancouver, British ColumbiaWeather: 69 degrees, 4% chance of precipitation, 4-mph winds

Argonauts vs. Lions Odds

Argonauts vs. Lions Odds Analysis

This game opened with the Lions as a 3-point favorite. The early money is still coming in on them, increasing the Lions to a 5.5-point favorite at some books. However, Draftkings is offering them at 4.5.

If you're leaning toward the Argos, they're listed at +5.5 at Caesars.

Argonauts vs. Lions Picks

Moneyline:Lions (-190)?????Spread:Lions - 4.5 (-110)????Over/Under:Over 49.5 (-110)?????

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Argonauts vs. Lions ML Pick

Lions (-190)

The Lions' Week 1 win may end up being their most impressive outing of the campaign statistically.

Nathan Rourke completed 90% of his pass attempts for 282 yards and three touchdowns. Running back James Butler was the recipient of two touchdown tosses while also rushing for 108 yards and another two scores.

Meanwhile, Argonauts running back Andrew Harris has looked good too, rushing for 87 yards during the team's lone game. But Toronto's quarterback play was a little inconsistent. McLeod Bethel-Thompson completed 71% of his attempts for 269 yards, but he threw an interception and only one touchdown pass. The Lions should run away with this one.

Argonauts vs. Lions ATS Pick

Lions -4.5 (-110)

Rourke has looked unstoppable. Not only was he productive through the air, but Rourke also rushed for 78 yards and two touchdowns during the Lions' victory. That’s the sixth-most single-game rushing yards in 2022 and the top mark from a quarterback.

Look for him to continue that top-tier play while often connecting with wide receiver Lucky Whitehead.

https://twitter.com/BCLions/status/1540065047715749893

Argonauts vs. Lions O/U Pick

Over 49.5 (-110)

The Lions’ home opener came against an Edmonton Elks team that's poor defensively. But don't take the Under in a Lions game until an opposing club proves they can be stopped.

The Argonauts are better positioned to slow them down, but I’m still confident the game goes Over 49.5. In fact, the Lions covered that spread by themselves in Week 1.

The Argonauts scored 20 in their opener, and Toronto should be able to hit that mark again. The Lions should need to score a more modest 30 points for the Over to hit.

Where to Bet on Argonauts-Lions Picks

Here are our top-rated sportsbooks:

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Argonauts-Lions picks made 6/23/2022 at 8:14 p.m. ET.