Let’s take a closer look at the MLB odds for this American League matchup at the O.co Coliseum, with the first pitch scheduled for 10:05 p.m. ET.
Check out our Wednesday Morning MLB Odds & Betting Lines Report.
New York is 3-2 on its current 10-game road trip, but it suffered a 6-4 loss to Oakland as +107 underdogs Tuesday, while going OVER the total for the first time in five contests.
The Yankees are 7-7 as road underdogs of +100 to +125 during the 2013 campaign, with the UNDER going 8-6 in that situation.
Oakland is tied with the Texas Rangers atop the AL West standings, as the club is a major league-best 19-5 since May 17, with the pitching staff compiling a 2.53 ERA in that span.
The Athletics are 38-17 as home favorites of -125 to -150 the last two-plus seasons, with the OVER going 31-23-1 in those 55 opportunities.
Yankees starting pitcher Phil Hughes (3-4, 4.80 ERA) picked up an impressive 6-1 road victory over the Seattle Mariners last time out, as he allowed a single run (zero earned) and three hits over seven frames.
The right-hander is 2-1 with a 3.44 ERA in six road efforts, issuing eight walks and striking out 31 batters in 36.2 combined innings.
In nine career games (six starts) versus the Athletics, Hughes has compiled a 3-1 record and 4.12 ERA, including a 4-2 home victory on May 4.
Athletics starting pitcher Dan Straily (3-2, 4.67 ERA) has led the club to four consecutive victories, as he didn’t earn a decision in a 5-4 road win over the Chicago White Sox last time out, allowing four runs and six hits over seven innings.
The right-hander has tallied an even 1-1 record and 5.14 ERA in four home appearances, with opposing hitters batting .256 against him.
Straily picked up a no decision in his only career effort against the Yankees on May 5, as he surrendered three runs and four hits over 5.1 frames.
I’m going to recommend that readers back the Yankees as one of their MLB picks Wednesday, as they’ve gone 9-4 in their last 13 road games versus a team with a winning record.
Oakland will likely be without the services of outfielder Yoenis Cespedes (questionable), who suffered a left hamstring injury in the series opener.
MLB Pick: New York Yankees +115
Not sold? Let our Free MLB Picks of the Day help convince you to back the Bronx Bombers as dogs today.