Let’s take a closer look at the MLB betting odds for this interleague matchup at Wrigley Field, with the first pitch scheduled for 8:05 p.m. ET.
Check out our Wednesday Morning MLB Odds & Betting Lines Report.
Troubles at first
Los Angeles suffered a 7-2 series-opening loss to Chicago as -138 road favorites Tuesday night, while pushing up against the betting total of 9.
Angels first baseman Albert Pujols is batting just .226 when playing in the field this season—compared to .264 when serving as the team’s designated hitter.
Since 2007, the club is 80-44 in interleague play, which happens to be the top mark in baseball over that span.
Chicago has won four games in a row, which is just single victory away from matching a season-high, as the squad looks to improve upon its 13-6 record versus American League opponents.
The Cubs are 9-13 as home underdogs of +100 to +125 this season, with the OVER going 11-9-2 in that situation.
Angels starting pitcher C.J. Wilson (8-6, 3.49 ERA) had his personal four-game win streak snapped last time out, as he suffered a 6-2 home loss to the Boston Red Sox, allowing three runs (one earned) and 10 hits over 6.2 innings.
The left-hander is 4-3 with a 4.64 ERA in nine road outings, issuing 25 walks and striking out 56 batters in 52.1 combined frames.
Wilson owns a 2-0 record and 3.94 ERA versus NL opponents since becoming a member of the Halos in 2012.
Cubs starting pitcher Jeff Samardzija (5-8, 3.54 ERA) has led the club to victory in four of his last five outings, but he suffered a 6-2 home loss to the Pittsburgh Pirates last time out, as he allowed five runs and nine hits over six frames.
The right-hander is 2-3 with a 4.47 ERA in nine home appearances, with opposing hitters batting .284 against him.
Samardzija will be making his first career start versus the Angels.
I’m going to recommend that readers back the Angels as one of their MLB picks Wednesday, as they’ve won eight of Wilson’s last 10 starts as a road favorite of -110 to -150.
MLB Pick: Los Angeles Angels -122