Let’s take a closer look at the MLB odds for this interleague matchup at U.S. Cellular Field, with the first pitch scheduled for 8:10 p.m. ET.
Check out our Wednesday Morning MLB Odds & Betting Lines Report.
New York has alternated wins and losses over its last four games, as it suffered a 5-4 setback to Chicago as +163 road underdogs Tuesday, while going OVER the total for a third consecutive contest.
The Mets are 2-5 as road underdogs of +100 to +125 this season, with the OVER going 6-0-1 in that situation.
Success at home in interleague play
Chicago has a losing 5-7 record against National League opponents this season, but the club has won 10 of its last 13 home series in interleague play.
The White Sox are 4-9 at home when the betting total is 8 to 8.5, with the UNDER going 6-4-3 in those 13 opportunities.
Mets starting pitcher Shaun Marcum (0-9, 5.76 ERA) is still searching for his first victory of the 2013 campaign, as he comes off a 5-3 road loss to the Atlanta Braves last time out, allowing five runs and six hits over 4.2 frames.
The right-hander is 0-4 with a 6.00 ERA in five road games (four starts), but has surrendered just one home run in 24 combined innings.
In five career starts versus the White Sox, Marcum has compiled a 3-0 record and 2.48 ERA, including a 2-0 mark and 2.35 ERA in three efforts at this ballpark.
White Sox starting pitcher John Danks (1-4, 5.40 ERA) has dropped back-to-back decisions, which includes an 8-4 road loss to the Minnesota Twins last time out, as he surrendered six runs and 12 hits over five frames.
The left-hander is 1-0 with a 2.57 ERA in two home outings, with opposing hitters batting just .149 against him.
Danks will be facing the Mets for the first time in his career.
I’m going to recommend that readers back the Mets as one of their MLB picks Wednesday, as the White Sox are 1-8 in their last nine games as favorites.
New York’s bullpen has also compiled an impressive 1.34 ERA in the last 10 games.
MLB Pick: New York Mets +120