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Drake Maye of the North Carolina Tar Heels rolls out against the Florida A&M Rattlers during the first half of their game at Kenan Memorial Stadium.
Drake Maye of the North Carolina Tar Heels rolls out against the Florida A&M Rattlers during the first half of their game at Kenan Memorial Stadium on August 27, 2022 in Chapel Hill, North Carolina. Photo by Grant Halverson/Getty Images via AFP.

Each week in college football, we’re identifying the top moneyline bets for building your bankroll. Read on for our top moneyline bets for Week 4 of the college football season.

In this week’s moneyline picks, we explore Auburn as a legitimate lock this week following its awful performance hosting Penn State. We also ride two explosive offenses matched up against big-name programs with serious concerns about moving the football.

Here are our top moneyline bets for Week 4 of the college football season (odds via DraftKings SportsbookFanDuel Sportsbook; pick confidence based on a 1-to-5-star scale).

Top College Football Moneyline Bets for Week 4

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Top College Football Week 4 Moneyline Predictions

Arkansas (+115) ★★★★

The Arkansas Razorbacks nearly allowed an unfathomable home upset by Bobby Petrino’s Missouri State in Week 3, but a furious rally of 21 fourth-quarter points saved their bacon - or rather, saved the Hogs from becoming bacon. Following that close call, I like Arkansas to make a statement at offensively challenged Texas A&M.

Beating Miami 17-9 at least allowed Jimbo Fisher to exhale, but I’m not sure he’ll have an answer for how to keep up with the Razorbacks offense until he resolves his evident quarterback quandary. Haynes King and Max Johnson have split the work for the Aggies, but have combined to lead the team to just 31 total points in two games against FBS foes.

Arkansas has scored 30-plus points in each of its three games, and though this will be its first road test of the season, the Hogs have averaged 29.4 points per game on the road since Sam Pittman took over as head coach in 2020. Texas A&M scoring 30 in a four-quarter football game simply isn’t in the range of outcomes at this juncture. 

North Carolina (-110) ★★★

Nothing we’ve seen from the Notre Dame offense suggests it can keep pace with the scoring prowess of North Carolina. The Irish’s lone cover of the season came in a defensive struggle at Ohio State. That won’t be the script this weekend in Chapel Hill.

The Tar Heels have averaged 50-plus points per game this season and are comfortable playing in the kind of shootout that would make Notre Dame squeamish. The Irish are averaging a shade above 300 yards of total offense per game this season, 110th in FBS.

Their total defense ranks top 50 in FBS, but it’s not adept enough to dictate the pace on the road against a UNC offense that ranks 25th in FBS in the fewest seconds per play. North Carolina expects star receiver Josh Downs to return from injury this week to further enhance the offense. UNC is 12-2 at home since the beginning of 2020 and should race past a Notre Dame team still straining to score points.

FanDuel offers UNC -110, while DraftKings has the line at -120 for the home team.

Auburn (-275) ★★★★★

After last week’s embarrassment against Penn State, it’s clear Bryan Harsin’s seat has never been warmer. His firing will have to wait, though, as taking the home-team Tigers for a bounceback against a struggling Missouri side should be free money in Week 4.

Eliah Drinkwitz’s Mizzou Tigers have looked like one of the most hapless Power Five offenses of the season. The offensive line play for Missouri has been dreadful, making a Week 2 trip to Manhattan, Kansas a lost cause from the jump. Missouri gritted out an ugly 34-17 win over FCS Abilene Christian this past week. Not encouraging.

Missouri is 2-8 on the road under Drinkwitz since 2020 and the average margin of defeat in those eight losses has been nearly three touchdowns (20.25). For all its many issues, Auburn is 6-1 outright when playing as a home favorite under Harsin. Favored by a touchdown, Auburn will handle this one at home.

Where to Bet on College Football Moneyline Picks

Here are our top-rated sportsbooks:

FanDuel Sportsbook
Caesars Sportsbook
DraftKings Sportsbook

SEE ALSO: All picksodds, and sports betting news. Be sure to check out’s community forums and betting tools.

College football moneyline picks made 9/19/2022 at 11:00 p.m. ET.