Skip to main content
AUBURN, ALABAMA - OCTOBER 30: Quarterback Matt Corral #2 of the Mississippi Rebels scrambles with the ball during the second quarter of their game against the Auburn Tigers at Jordan-Hare Stadium on October 30, 2021 in Auburn, Alabama. Michael Chang/Getty Images/AFP (Photo by Michael Chang / GETTY IMAGES NORTH AMERICA / Getty Images via AFP)

November is here, and college football is coming to a close. We offer up our best early college football parlay picks for Week 10 as we try to maximize our returns in what's left of the season.

With November finally here, it is time to get serious in the world of college football. Teams are making a push to win their conferences and make it to the College Football Playoff, and things are getting interesting.

No one knows what to expect from the top teams anymore, but we have more information now than ever. Teams are showing their true colors, and the title contenders are distancing themselves from the rest of the college football field.

There are plenty of ranked teams that face off in Week 10, and there are plenty of intriguing early lines. With that in mind, let’s take a look at what picks we can target for a college football parlay this weekend. 

Here’s a look at my top early parlay picks for Week 10 of college football action (odds via FanDuel Sportsbook; pick confidence based on a 1-to-5-star scale):

Week 10 Parlay Picks

Wake Forest +2.5 (-105) vs. North Carolina

Wake Forest finally needs to be taken seriously. The Demon Deacons have been overlooked all season, but they keep producing wins. QB Sam Hartman is a dark horse to win the Heisman Trophy, and the Deacons are charging through the ACC.

North Carolina has been incredibly inconsistent this season. The Tar Heels have been successfully running the ball, but turnovers are a concern, and they have flopped offensively on multiple occasions. QB Sam Howell has not lived up to the hype, which has hurt the team's overall projection.

If North Carolina wins by a wide margin, it will be because of the run game. However, Wake Forest can put points on the board with the best of them, so I still think the Demon Deacons have a chance to win it outright.

Due to the risk of running a parlay, I will stick with the spread instead of the moneyline (+116) for this week.

Confidence Meter: ???

SEE ALSO: Top College Football Week 10 Opening Lines and Picks

Missouri vs. Georgia Under 59.5 (-115) 

Georgia has a ridiculous spread (-37.5, -114) and moneyline (-100000) for this game. Neither line has value, so we'll instead look at the total.

No one has scored more than 13 points against the Georgia defense and this game will have a similar result on that side of the ball. Missouri has a worse offense than other teams who have struggled against the Bulldogs.

Missouri barely beat Vanderbilt 37-28 last week, and the Tigers won’t be able to do much in Week 10. If the Over were to hit, it would be because the Bulldogs scored at least 50 points. That is possible, but it is more likely the backups will let off in the second half.

Confidence Meter: ??

Liberty vs. Ole Miss (-325)

Ole Miss has one of the best offenses in college football, but its defense struggles against dynamic athletes. Playing against Libert QB Malik Willis will be no easy feat for the Rebels, and QB Matt Corral’s (ankle) injury concerns don’t help matters.

However, this is not about locking in a win for the parlay. If you want to do that, add the moneyline of Georgia, Alabama or Ohio State. This is about adding value, and it exists with the Ole Miss moneyline. 

Ole Miss will be looking to make a statement at home. Head coach Lane Kiffin will open up the playbook against Liberty and try to boost Corral’s draft stock. Assuming Corral is at least 90 percent healthy, the Rebels should have much better odds than this. This is a value play.

If reports suggest Corral isn't fully healthy, then reconsider this. Until then, expect the Ole Miss moneyline to be a great addition to your parlay.

Confidence Meter: ????

Combined Odds: +377

Confidence Meter: ???

SEE ALSO: All college football Week 10 odds and lines

Picks made on 11/01/21 at 5:40 p.m. ET