Why is Isner such a favorite over Querrey? -163 and +130 for Querrey
Their H2H is 4-1 in favor of Querrey, 3-1 on hard courts., beating Isner 2times in straights sets last year.
Isner has not played a match this season and can be a bit rusty while Querrey got some match time against Bedene yesterday.
Both guys have big serves and weak return games, but I think Querrey definitely has the edge here on the returns and baseline play.
Querrey also caught Isner at an opportune time last year, after a long, grueling stretch of matches and tournaments. Isner should be fresh and ready to exact a bit of revenge on a fast court.