Im rolling with Seppi +110 here. Seppi 6-4 at Paris Masters overall and went deep 2 years ago, seems to like this tournament and playing style. Kohlschreiber is 5-5 overall here and has been ousted in the first round here a couple of times. Seppi also has played Kohlschreiber here a few years back and won in straight sets.
Neither player has been in outstanding form the past couple months however, so this really is a toss up. Im just going with my gut and what research/stats are saying.