Villarreal news
Villarreal are in even greater need of a victory than City after the defeat in Manchester left them rooted to the bottom of Group A without a point.
City have four points, Napoli five and Bayern seven so Villarreal probably need to win all three of their remaining games to advance to the knockout stages.
But coach Juan Carlos Garrido has not been helped by an injury crisis which has seen several key players struck down.
Star striker Giuseppe Rossi has been ruled out for six months after suffering cruciate ligament damage in last week's 3-0 loss to Real Madrid in the Primera Liga.
With the likes of Nilmar, Marco Ruben, Marcos Senna, Javier Camunas, Cani and Cristian Zapata also sidelined, Garrido has been forced to call up young strikers Joselu and Adolfo Enriquez from the B and C teams.
Villarreal did at least manage to beat Rayo Vallecano 2-0 at the weekend to end a run of seven straight defeats in all competitions.