1. #1
    guitarjosh
    guitarjosh's Avatar Become A Pro!
    Join Date: 12-25-07
    Posts: 4,652
    Betpoints: 4036

    The Key to Defeating COVID-19 Already Exists. We Need to Start Using It

    https://www.newsweek.com/key-defeati...pinion-1519535

    On 7/23/20 at 7:00 AM EDT
    Harvey A. Risch, MD, PhD , Professor of Epidemiology, Yale School of Public Health

    As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are dying unnecessarily. Fortunately, the situation can be reversed easily and quickly.

    I am referring, of course, to the medication hydroxychloroquine. When this inexpensive oral medication is given very early in the course of illness, before the virus has had time to multiply beyond control, it has shown to be highly effective, especially when given in combination with the antibiotics azithromycin or doxycycline and the nutritional supplement zinc.

    On May 27, I published an article in the American Journal of Epidemiology (AJE) entitled, "Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis." That article, published in the world's leading epidemiology journal, analyzed five studies, demonstrating clear-cut and significant benefits to treated patients, plus other very large studies that showed the medication safety.

    Physicians who have been using these medications in the face of widespread skepticism have been truly heroic. They have done what the science shows is best for their patients, often at great personal risk. I myself know of two doctors who have saved the lives of hundreds of patients with these medications, but are now fighting state medical boards to save their licenses and reputations. The cases against them are completely without scientific merit.

    Since publication of my May 27 article, seven more studies have demonstrated similar benefit. In a lengthy follow-up letter, also published by AJE, I discuss these seven studies and renew my call for the immediate early use of hydroxychloroquine in high-risk patients. These seven studies include: an additional 400 high-risk patients treated by Dr. Vladimir Zelenko, with zero deaths; four studies totaling almost 500 high-risk patients treated in nursing homes and clinics across the U.S., with no deaths; a controlled trial of more than 700 high-risk patients in Brazil, with significantly reduced risk of hospitalization and two deaths among 334 patients treated with hydroxychloroquine; and another study of 398 matched patients in France, also with significantly reduced hospitalization risk. Since my letter was published, even more doctors have reported to me their completely successful use.

    My original article in the AJE is available free online, and I encourage readers—especially physicians, nurses, physician assistants and associates, and respiratory therapists—to search the title and read it. My follow-up letter is linked there to the original paper.

    Beyond these studies of individual patients, we have seen what happens in large populations when these drugs are used. These have been "natural experiments." In the northern Brazil state of Pará, COVID-19 deaths were increasing exponentially. On April 6, the public hospital network purchased 75,000 doses of azithromycin and 90,000 doses of hydroxychloroquine. Over the next few weeks, authorities began distributing these medications to infected individuals. Even though new cases continued to occur, on May 22 the death rate started to plummet and is now about one-eighth what it was at the peak.

    Hydroxychloroquine tablets GEORGE FREY/AFP via Getty Images
    A reverse natural experiment happened in Switzerland. On May 27, the Swiss national government banned outpatient use of hydroxychloroquine for COVID-19. Around June 10, COVID-19 deaths increased four-fold and remained elevated. On June 11, the Swiss government revoked the ban, and on June 23 the death rate reverted to what it had been beforehand. People who die from COVID-19 live about three to five weeks from the start of symptoms, which makes the evidence of a causal relation in these experiments strong. Both episodes suggest that a combination of hydroxychloroquine and its companion medications reduces mortality and should be immediately adopted as the new standard of care in high-risk patients.

    Why has hydroxychloroquine been disregarded?

    First, as all know, the medication has become highly politicized. For many, it is viewed as a marker of political identity, on both sides of the political spectrum. Nobody needs me to remind them that this is not how medicine should proceed. We must judge this medication strictly on the science. When doctors graduate from medical school, they formally promise to make the health and life of the patient their first consideration, without biases of race, religion, nationality, social standing—or political affiliation. Lives must come first.

    Second, the drug has not been used properly in many studies. Hydroxychloroquine has shown major success when used early in high-risk people but, as one would expect for an antiviral, much less success when used late in the disease course. Even so, it has demonstrated significant benefit in large hospital studies in Michigan and New York City when started within the first 24 to 48 hours after admission.

    In fact, as inexpensive, oral and widely available medications, and a nutritional supplement, the combination of hydroxychloroquine, azithromycin or doxycycline, and zinc are well-suited for early treatment in the outpatient setting. The combination should be prescribed in high-risk patients immediately upon clinical suspicion of COVID-19 disease, without waiting for results of testing. Delays in waiting before starting the medications can reduce their efficacy.

    Third, concerns have been raised by the FDA and others about risks of cardiac arrhythmia, especially when hydroxychloroquine is given in combination with azithromycin. The FDA based its comments on data in its FDA Adverse Event Reporting System. This reporting system captured up to a thousand cases of arrhythmias attributed to hydroxychloroquine use. In fact, the number is likely higher than that, since the reporting system, which requires physicians or patients to initiate contact with the FDA, appreciably undercounts drug side effects.

    But what the FDA did not announce is that these adverse events were generated from tens of millions of patient uses of hydroxychloroquine for long periods of time, often for the chronic treatment of lupus or rheumatoid arthritis. Even if the true rates of arrhythmia are ten-fold higher than those reported, the harms would be minuscule compared to the mortality occurring right now in inadequately treated high-risk COVID-19 patients. This fact is proven by an Oxford University study of more than 320,000 older patients taking both hydroxychloroquine and azithromycin, who had arrhythmia excess death rates of less than 9/100,000 users, as I discuss in my May 27 paper cited above. A new paper in the American Journal of Medicine by established cardiologists around the world fully agrees with this.

    In the future, I believe this misbegotten episode regarding hydroxychloroquine will be studied by sociologists of medicine as a classic example of how extra-scientific factors overrode clear-cut medical evidence. But for now, reality demands a clear, scientific eye on the evidence and where it points. For the sake of high-risk patients, for the sake of our parents and grandparents, for the sake of the unemployed, for our economy and for our polity, especially those disproportionally affected, we must start treating immediately.

    Harvey A. Risch, MD, PhD, is professor of epidemiology at Yale School of Public Health.

    The views expressd in this article are the writer's own.

  2. #2
    pologq
    Only 2 Girls Short of a 3-Some
    pologq's Avatar SBR PRO
    Join Date: 10-07-12
    Posts: 7,416
    Betpoints: 710

    interesting article

    my dad takes hydroxychloroquine. we believe he had the virus and this helped him but no way to be 100% sure because it was end of jan and early february and the antibody test in june showed no antibodies. some docs say it means he did not have it and some say it was because it is long after and maybe antibodies were gone.

    i had antibodies in may. this was prob after getting sick with covid in the middle of feb and early march based on my symptoms. i assume it was from my dad cause our coughs were the same but it might not have been. you never know. maybe that was not covid and i had covid later with minimal symptoms.

    my dad has RA and some liver issues. his hepatic doctor told him it was probably the hydroxychloroquine that saved him if he indeed had it given he has an auto-immune disease and 25% of a scarred liver. she said though there is no way to be sure.

    i do believe this medicine works for Covid. too many coincidences given my dad's symptoms and how he was able to fight with no hospital stay given his other conditions. she said it would be 99% sure he would have been in the hospital if it was covid and no hydroxychloroquine was present. she believes it helps against covid from her own research and such.

  3. #3
    EmpireMaker
    EmpireMaker's Avatar SBR PRO
    Join Date: 06-18-09
    Posts: 13,688
    Betpoints: 12

    That crap doesn't work for covid, only malaria.

  4. #4
    RudyRuetigger
    Retired
    RudyRuetigger's Avatar SBR PRO
    Join Date: 08-24-10
    Posts: 53,495

    Quote Originally Posted by EmpireMaker View Post
    That crap doesn't work for covid, only malaria.
    tell that to the fukkin studies


    holy fukk you democrats are crazy
    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/26/2020

    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/19/2020

    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/15/2020


  5. #5
    jjgold
    Update your status
    jjgold's Avatar Horses Moderator
    Join Date: 07-20-05
    Posts: 349,202
    Betpoints: 845

    Good idea

    Where do you buy?

  6. #6
    RudyRuetigger
    Retired
    RudyRuetigger's Avatar SBR PRO
    Join Date: 08-24-10
    Posts: 53,495

    https://townhall.com/tipsheet/katiep...again-n2572997


    “A surprising new study found the controversial antimalarial drug hydroxychloroquine helped patients better survive in the hospital,” CNN reports. “A team at Henry Ford Health System in southeast Michigan said Thursday their study of 2,541 hospitalized patients found that those given hydroxychloroquine were much less likely to die. Dr. Marcus Zervos, division head of infectious disease for Henry Ford Health System, said 26% of those not given hydroxychloroquine died, compared to 13% of those who got the drug.” The team reviewed everyone treated in the hospital system since March."





    there you go democrat fukkwads

    i highlighted cnn changing their tune
    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/26/2020

    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/19/2020

    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/15/2020


  7. #7
    seaborneq
    It's time to collect
    seaborneq's Avatar SBR PRO
    Join Date: 09-08-06
    Posts: 20,144
    Betpoints: 7760

    How do we keep from getting it so that treatment is not needed? Otherwise just send each household a bottle of the magic potion and lets move forward. This is going on 6 months and we are no better off than we were in mid March. Probably worse off now. The key is too keep people from getting it because each person’s body reacts to it differently.

  8. #8
    guitarjosh
    guitarjosh's Avatar Become A Pro!
    Join Date: 12-25-07
    Posts: 4,652
    Betpoints: 4036

    Quote Originally Posted by RudyRuetigger View Post
    tell that to the fukkin studies


    holy fukk you democrats are crazy
    Yeah, they have to politicize everything. You have to wonder how many died because of the left pushing flawed studies to make Trump look bad.
    Points Awarded:

    Bandit gave guitarjosh 2 Betpoint(s) for this post.


  9. #9
    Sanity Check
    A Rising Tide Lifts All Ships
    Sanity Check's Avatar Become A Pro!
    Join Date: 03-30-13
    Posts: 8,404
    Betpoints: 10122

    Quote Originally Posted by EmpireMaker View Post
    That crap doesn't work for covid, only malaria.

    Published online 2005 Aug 22. doi: 10.1186/1743-422X-2-69
    PMCID: PMC1232869
    PMID: 16115318


    Chloroquine is a potent inhibitor of SARS coronavirus infection and spread


    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/



    Leftists are always the least informed and least knowledgeable when it comes to science.



  10. #10
    Bandit
    Update your status
    Bandit's Avatar Become A Pro!
    Join Date: 04-24-14
    Posts: 362
    Betpoints: 7590

    Quote Originally Posted by guitarjosh View Post
    Yeah, they have to politicize everything. You have to wonder how many died because of the left pushing flawed studies to make Trump look bad.
    Your right. Start with Coumo the NY IDIOT who sooo calculated (according to him the fuwker) the minimal effect of moving all those Seniors back into the Nursing Homes. What a Narcissistic prick.

  11. #11
    RudyRuetigger
    Retired
    RudyRuetigger's Avatar SBR PRO
    Join Date: 08-24-10
    Posts: 53,495

    Check in empire maker you dumb mother fukker

    i love you clowns

    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/26/2020

    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/19/2020

    175 pts

    3-QUESTION
    SBR TRIVIA WINNER 10/15/2020


  12. #12
    Ghenghis Kahn
    Ghenghis Kahn's Avatar SBR PRO
    Join Date: 01-02-12
    Posts: 17,668
    Betpoints: 854

    Remdesivir treatment cost over $3000... Hydroxychlorquine (generic) $150 for 60 pills of 200mg.

    You don't have to be a genius to see which one is more profitable for big pharma.

  13. #13
    maggiethebestdog
    maggiethebestdog's Avatar Become A Pro!
    Join Date: 12-21-13
    Posts: 6,082
    Betpoints: 6785

    Quote Originally Posted by RudyRuetigger View Post
    Check in empire maker you dumb mother fukker

    i love you clowns

    Hey Rudy, chico said you were 6 ft and 145 lbs

    I know he has dementia, but is that true???

    No wonder you can only drive the ball 200

  14. #14
    turbobets
    turbobets's Avatar Become A Pro!
    Join Date: 01-13-06
    Posts: 664
    Betpoints: 8841

    Quote Originally Posted by RudyRuetigger View Post
    CNN reports
    Good job Rudy maybe you convinced a few from the "their truth over facts crowd."

  15. #15
    EmpireMaker
    EmpireMaker's Avatar SBR PRO
    Join Date: 06-18-09
    Posts: 13,688
    Betpoints: 12

    Here's the study, you Trumpers are a penetrating cult :
    Today, the U.S. Food and Drug Administration (FDA) revoked the emergency use authorization (EUA) that allowed for chloroquine phosphate and hydroxychloroquine sulfate donated to the Strategic National Stockpile to be used to treat certain hospitalized patients with COVID-19 when a clinical trial was unavailable, or participation in a clinical trial was not feasible. The agency determined that the legal criteria for issuing an EUA are no longer met. Based on its ongoing analysis of the EUA and emerging scientific data, the FDA determined that chloroquine and hydroxychloroquine are unlikely to be effective in treating COVID-19 for the authorized uses in the EUA. Additionally, in light of ongoing serious cardiac adverse events and other potential serious side effects, the known and potential benefits of chloroquine and hydroxychloroquine no longer outweigh the known and potential risks for the authorized use. This is the statutory standard for issuance of an EUA. The Biomedical Advanced Research and Development Authority (BARDA) within the U.S. Department of Health and Human Services originally requested the EUA covering chloroquine and hydroxychloroquine, and the FDA granted the EUA on March 28, 2020 based on the science and data available at the time. Today, in consultation with the FDA, BARDA sent a letter to the FDA requesting revocation of the EUA based on up to date science and data.
    “We’ve made clear throughout the public health emergency that our actions will be guided by science and that our decisions may evolve as we learn more about the SARS-CoV-2 virus, review the latest data, and consider the balance of risks versus benefits of treatments for COVID-19,” said FDA Deputy Commissioner for Medical and Scientific Affairs Anand Shah, M.D. “The FDA always underpins its decision-making with the most trustworthy, high-quality, up-to-date evidence available. We will continue to examine all of the emergency use authorizations the FDA has issued and make changes, as appropriate, based on emerging evidence.”
    The FDA has a responsibility to regularly review the appropriateness of an EUA, and as such, the agency will review emerging information associated with the emergency uses for the authorized products. Recent results from a large randomized clinical trial in hospitalized patients, a population similar to the population for which chloroquine and hydroxychloroquine were authorized for emergency use, demonstrated that hydroxychloroquine showed no benefit on mortality or in speeding recovery. This outcome was consistent with other new data, including data showing that the suggested dosing regimens for chloroquine and hydroxychloroquine are unlikely to kill or inhibit the virus that causes COVID-19. The totality of scientific evidence currently available indicate a lack of benefit.
    “While additional clinical trials continue to evaluate the potential benefit of these drugs in treating or preventing COVID-19, we determined the emergency use authorization was no longer appropriate. This action was taken following a rigorous assessment by scientists in our Center for Drug Evaluation and Research,” said Patrizia Cavazzoni, M.D., acting director of the FDA’s Center for Drug Evaluation. “We remain committed to using every tool at our disposal in collaboration with innovators and researchers to provide sick patients timely access to appropriate new therapies. Our decisions will always be based on objective and rigorous evaluation of the scientific data.This will never change.”
    Chloroquine and hydroxychloroquine are both FDA-approved to treat or prevent malaria. Hydroxychloroquine is also approved to treat autoimmune conditions such as chronic discoid lupus erythematosus, systemic lupus erythematosus in adults, and rheumatoid arthritis. Both drugs have been prescribed for years to help patients with these debilitating, or even deadly, diseases, and FDA has determined that these drugs are safe and effective when used for these diseases in accordance with their FDA-approved labeling. Of note, FDA approved products may be prescribed by physicians for off-label uses if they determine it is appropriate for treating their patients, including during COVID.
    The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.



    Quote Originally Posted by RudyRuetigger View Post
    tell that to the fukkin studies




    holy fukk you democrats are crazy

  16. #16
    EmpireMaker
    EmpireMaker's Avatar SBR PRO
    Join Date: 06-18-09
    Posts: 13,688
    Betpoints: 12

    Trump tells you morons to eat fish bowl cleaner and you penetrating do it.

  17. #17
    Goat Milk
    Goat Milk's Avatar Become A Pro!
    Join Date: 03-24-10
    Posts: 23,209
    Betpoints: 107

    I think the Z pack (azithmo) has been shown to be more effective for covid patients than hydrochloroquine, if you're judging each one on it's own, and I think most patients can recover from the z pack + zinc.

  18. #18
    guitarjosh
    guitarjosh's Avatar Become A Pro!
    Join Date: 12-25-07
    Posts: 4,652
    Betpoints: 4036

    Quote Originally Posted by EmpireMaker View Post
    Here's the study, you Trumpers are a penetrating cult :
    From the OP
    Second, the drug has not been used properly in many studies. Hydroxychloroquine has shown major success when used early in high-risk people but, as one would expect for an antiviral, much less success when used late in the disease course. Even so, it has demonstrated significant benefit in large hospital studies in Michigan and New York City when started within the first 24 to 48 hours after admission.

  19. #19
    guitarjosh
    guitarjosh's Avatar Become A Pro!
    Join Date: 12-25-07
    Posts: 4,652
    Betpoints: 4036

    Quote Originally Posted by EmpireMaker View Post
    Trump tells you morons to eat fish bowl cleaner and you penetrating do it.

    I'll listen to a professor of epidemiology at Yale.

  20. #20
    EmpireMaker
    EmpireMaker's Avatar SBR PRO
    Join Date: 06-18-09
    Posts: 13,688
    Betpoints: 12

    You listen to a moron scammer that thinks the only way he can be re-elected is to deny COVID exists while personally profiting from a drug he and his cronies bought stock in (and then he promoted the hell out of).

  21. #21
    EmpireMaker
    EmpireMaker's Avatar SBR PRO
    Join Date: 06-18-09
    Posts: 13,688
    Betpoints: 12

    A harsh lesson in the reality of COVID-19

    Jul 24, 2020 | 219


    For Tony Green, the coronavirus pandemic was just a ‘scamdemic’ — until truth hit home hard

    Imagine the sound and vibration of an old-fashioned electric heater going through your whole body. Imagine gasping for air with every step you take. Imagine rubbing Icy Hot all over your head to soothe a painful headache. Imagine your eyes in a bowl of water while you’re still seeing through them. Imagine collapsing and waking up in the ER only to find out COVID-19 attacked your central nervous system, and the doctor had just saved you from a stroke.
    If that were the worst of it, it would be bad enough. But that’s not the worst of it. This is the story of one family’s harrowing fight with COVID-19.
    Full disclosure: I am a gay conservative, someone that often juggles persecution for my sexuality while being true to my values. Such a combination requires a lot of tenacity to earn respect from either group.
    I admit I voted for Donald Trump in 2016. I admit traveling deep into the conspiracy trap over COVID-19. All the defiant behavior of Trump’s more radical and rowdy cult followers, I participated in it. I was a hard-ass that stood up for my “God-given rights.”
    In great haste, I began prognosticating the alphabet soup about this “scamdemic.” I believed the virus to be a hoax. I believed the mainstream media and the Democrats were using it to create panic, crash the economy and destroy Trump’s chances at re-election.
    And so, believing the pandemic to be a hoax, my partner and I hosted family members on Saturday, June 13. On Sunday, June 14, I woke up sick.
    By Monday, June 15, my partner and my parents were all sick. That same Monday, my in-laws traveled to witness the birth of their first grandchild. They took with them my father-in-law’s mother and one of my partner’s sisters. That night my father-in-law became ill. Then my mother-in-law and their daughter began feeling sick. So they cut their trip short.
    Two days later, my father-in-law’s mother got sick. The new mommy and daddy got sick, too. We all tested positive for COVID-19. Only the newborn was spared.
    My father-in-law and I both went to the hospital on June 24. The virus had attacked my central nervous system, and the staff stopped me from having a stroke.
    My father-in-law’s mother was admitted a day later. On July 1, she died of COVID-19/pneumonia. The chaplain wanted the family to break the news to my father-in-law, and he learned how his mother lay on her deathbed and then drifted off without any family by her side, even though he was in the room next to hers.
    On the day of her funeral, which was July 14, five more of our family members tested positive for the virus. That evening, my father-in-law was put on a ventilator.
    You cannot imagine the guilt I feel, knowing that I hosted the gathering that led to so much suffering. You cannot imagine my guilt at having been a denier, carelessly shuffling through this pandemic, making fun of those wearing masks and social distancing. You cannot imagine my guilt at knowing that my actions convinced both our families it was safe when it wasn’t.
    For those who deny the virus exists or who downplay its severity, let me assure you: The coronavirus is very real and extremely contagious. Before you even know you have it, you’ve passed it along to your friends, family, coworkers and neighbors.
    And now, husbands, wives and children are being separated. The sick are taking care of the sick while those without symptoms are self-quarantining. I am aware of how my bias could discredit me with some, but trust me, you do not want this virus. And you do not want your loved ones suffering and dying from this because you are taking a “political stand” or protecting the economy over their lives.
    We are all at the precipice of a common heartache.
    The next time you’re put out because your favorite spots are closed or because they won’t let you enter without wearing a mask, and you decide to defy them rather than comply because you’re defending your rights and freedoms from being trampled, just remember: Your family and friends may be next.
    Is that too harsh? Try imagining someone you care about on life support. Try being the one to pick the only 10 people allowed to attend a funeral for a loved one. But don’t fret; you’ve got time to ponder, because the mortuary is booked out for at least a week.
    Now imagine one more thing: That pool party, the mixer or family reunion you’re pushing for resulting in you being cold and alone in a hospital bed, fighting for your life. Imagine the only human contact you feel is a stranger’s rubber glove giving you medication, checking your vitals and changing your diaper.
    That is exactly what has happened to our family.
    America, this is not going to go away without sacrifice. Either way, we are going to pay a price. Governments are faced with making difficult decisions, and they cannot appease and satisfy everyone.
    But to do nothing is to be foolish. To ignore or question the validity of this virus, its contagiousness or the consequences of selfish attitudes is — at this stage — completely stupid.
    I am calling myself out first, but now this is personal, and I fell on my sword. And I promise you, if we continue being more worried about the disruption to our lives than we are about stopping this virus, not one American will be spared.
    Not one.

  22. #22
    guitarjosh
    guitarjosh's Avatar Become A Pro!
    Join Date: 12-25-07
    Posts: 4,652
    Betpoints: 4036

    Quote Originally Posted by EmpireMaker View Post
    You listen to a moron scammer that thinks the only way he can be re-elected is to deny COVID exists while personally profiting from a drug he and his cronies bought stock in (and then he promoted the hell out of).
    I didn't know that the professor of epidemiology at Yale was running for reelection.

  23. #23
    pavyracer
    MOLON LABE
    pavyracer's Avatar SBR PRO
    Join Date: 04-12-07
    Posts: 69,180
    Betpoints: 6613


Top