I know both are on the road and playing division rivals that need to win however Chiefs did play Broncos close at home and the Cardinals defense is solid even though the offense is a non factor and can force turnovers. So is either one worth a small play?
The Niners defense sure has been poor the last game and a half. How much of that is due to the absence of Justin Smith? (who isn't playing in this game) and how much is due to the fact that they were on the road back to back at 2 of the toughest places to play? Tough to say, but might be worth a small play on Az.
Zero chance Chiefs wins. Yes Denver only beat the Chiefs by 8 points in Kansas city. But the Broncos also kicked 3 field goals in the redzone, missing two easy ones. The Broncos will score touchdowns at home in the Redzone this time around. Denver will beat the Chiefs 38-6.
It's the NFL, so anything is "possible"...but it seems highly unlikely for the reasons that you've mentioned...both teams on the road, playing good teams who have something to play for.