McFadden most likely still out.
SD only gives out average 120 rushing yards per game so I doubt that Bush will be able to break loose on them, which will probably mean they will resort to the passing game and we all know Palmer still needs to polish out a few of those plays before he can get in to proper rhythm.
PLUS SD only gives out about 200yds passing (with the exception of Rodgers, who seems to be able to pass the ball on any team). On the other hand the Raiders are pretty much giving the house away, allowing almost 250 pass yards and 150 rushing yards avg per game...
The only way I see the Raiders win this is if they get Campbell and McFadden back... and that isn't going to happen any time soon, even if Campbell is a quick healer.
But I'd like to be proven wrong... as I'm not very fond of SD