I love playing trends and here are a couple I found for week 2:

1) Play a road team after a close loss (1-3 points) in game 2 of the preseason (73% win)

Week 2: Miami @ Jacksonville
Houston @ New Orleans
Green Bay @ Seattle

2) Play team in its third game vs. team in its second game (75% win)

Week 2: Dallas @ San Diego
Philadelphia @ Cincinnati

Depending on the spread I really like these trends and will be playing them.