If I was betting, I'd be hammering the piss out of this one. I look at what the Detroit offense did last week on the road vs a tough Jets defense and I just can't imagine the Lioks don't hang 31+ on the bills at home. Megatron should have an enormous game after last week's struggles. Ebron is really showing some life and Bush will get a lot of touches today. Speed demons on the field today. Also, Orton is an upgrade over Manuel. This benching is a blessing in disguise for Bills fans. Watkins back, new QB with proven track record and probably forced to play catch up.
Lions / Bills Over 43 (-110)
Fade away boys, if you dare. Goodluck.