I am taking the Colts here. Andrew Luck is pretty good and already playing like a 10 year vet in just his second season. 7.5 is a LOT OF POINTS for a home dog, especially one with offensive weapons that the Colts have. T.Y. Hilton could go off for a 50 yard TD reception at anytime. Fleener is decent catching balls up the middle. T-Rich can pound it in for 3 yards out from a touchdown and Donald Brown isn't half bad either.
Manning and that Broncos offense are juggernauts but Colts at home can hang. Only problem is Jim Irsay opening his big fat mouth and possibly making Peyton look like an overrated scrub with his comments might fuel Peyton to beat Irsay's team especially hard this week. I don;t see Luck wanting that to happen though.
Taking Colts +7.5.