Actually, the proposition of another #16 seed beating a #1 seed in the next 10 years would be a favorite vs. it not happening. If every #1 seed had a 98% chance of winning its game the next 40 tries (and there would often be cases where they were less than 98% in reality, but almost never more than 98%), the chance of a #16 seed winning at least once in the next 40 tries would be 55%. Fact is, it was amazing (although not earth shattering) it hadn't happened before today, but that's just variance.