I believe Cotto will stop Margaritto. Ods are + 300. Remember after the Pacquiao fight, Margarito wasnt allowed to fight ever again. But there is too much money involved in a Cotto-Margarito rematch.
I wouldnt be suprised if they paid people to make sure Margaritto would get his boxing license back , even though he isnt 100% healthy to box. So +300 for Cotto stopping a one eyed Margaritto is a smart bet IMO.